| Identification | Back Directory | [Name]
TC-E 5001 | [CAS]
865565-29-3 | [Synonyms]
TC-E 5001
TC E 5001,TCE 5001
3-(4-Methoxyphenyl)-5-[[[4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazole | [Molecular Formula]
C20H19N5O3S | [MDL Number]
MFCD14811685 | [MOL File]
865565-29-3.mol | [Molecular Weight]
409.46 |
| Chemical Properties | Back Directory | [Boiling point ]
631.5±65.0 °C(Predicted) | [density ]
1.35±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble to 100 mM in DMSO | [form ]
Powder | [pka]
1.43±0.10(Predicted) | [color ]
white |
| Hazard Information | Back Directory | [Uses]
TC-E 5001 is a wnt pathway antagonist, which inhibits tankyrases 1 and 2 via novel adenosine pocket binding. | [Biological Activity]
Cell permeable: yes''Primary Target
TNKS1/PARP5a and TNKS2/PARP5b''Reversible: yes | [IC 50]
TNKS1: 79 nM (Ki); TNKS2: 28 nM (Ki) | [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|