| Identification | Back Directory | [Name]
TA-8995 | [CAS]
866399-87-3 | [Synonyms]
AMG899
TA-8995
AMG 899
DEX-001
Obicetrapib (free base)
Obicetrapib (AMG-899,TA-8995)
AMG 899;TA 8995;AMG899;TA8995;
4-[(2-{[3,5-bis(trifluoromethyl)benzyl][(2R,45)-1-(ethoxycarbonyl)-2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-yl]amino}pyrimidin-5-yl)oxy]butanoic acid
1(2H)-Quinolinecarboxylic acid, 4-[[[3,5-bis(trifluoromethyl)phenyl]methyl][5-(3-carboxypropoxy)-2-pyrimidinyl]amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-ethyl ester, (2R,4S)- | [Molecular Formula]
C32H31F9N4O5 | [MDL Number]
MFCD30533470 | [MOL File]
866399-87-3.mol | [Molecular Weight]
722.6 |
| Chemical Properties | Back Directory | [Boiling point ]
692.5±65.0 °C(Predicted) | [density ]
1.394±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.52±0.10(Predicted) | [color ]
White to light yellow | [InChIKey]
NRWORBQAOQVYBJ-GJZUVCINSA-N | [SMILES]
N1(C(OCC)=O)C2=C(C=C(C(F)(F)F)C=C2)[C@@H](N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C2=NC=C(OCCCC(O)=O)C=N2)C[C@H]1CC |
| Hazard Information | Back Directory | [Uses]
Obicetrapib, is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors, can increase the concentration of high-density lipoprotein cholesterol (HDL-C), which might help to reduce the risk of cardiovascular diseases. |
|
| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
| Company Name: |
Wuhan Topule
|
| Tel: |
+86-02787215551 19945035818 |
| Website: |
http://www.topule.com/ |
|