| Identification | More | [Name]
Sodium D-pantothenate | [CAS]
867-81-2 | [Synonyms]
D-PANTOTHENIC ACID, NA SALT
D-PANTOTHENIC ACID SODIUM
D(+)-PANTOTHENIC ACID SODIUM SALT
D-PANTOTHENIC ACID SODIUM SALT
(r)-n-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-beta-alanine monosodium salt
SODIUM D-PANTOTHENATE
SODIUM PANTHOTENATE
SODIUM PANTOTHENATE
beta-alanine,n-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-,monosodiumsalt,(t
heta)-
monosodiumsalt,d-pantothenicaci
N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-,monosodiumsalt,(R)-.beta.-Alanine
n-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-,monosodiumsalt,(r)-beta-alanin
n-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-,monosodiumsalt,(theta)-beta-alanin
pantothenicacid,sodiumsalt
sodiumpantothenicacid
Pantothenic acid sodium
D-PANTOTHENIC ACID SODIUM SALT 97+%
SdoiumPantothenate,>97.5%
PantothenicAcid,SodiumSalt>97.5% | [EINECS(EC#)]
212-768-6 | [Molecular Formula]
C9H16NNaO5 | [MDL Number]
MFCD00002767 | [Molecular Weight]
241.22 | [MOL File]
867-81-2.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R48:Danger of serious damage to health by prolonged exposure.
R41:Risk of serious damage to eyes.
R37/38:Irritating to respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S22:Do not breathe dust . | [HS Code ]
29241990 | [Hazardous Substances Data]
867-81-2(Hazardous Substances Data) |
| Questions And Answer | Back Directory | [Description]
Sodium D-pantothenate is the sodium salt of the biological active
enantiomer of pantothenic acid (vitamin B5). As D-pantothenic acid
is a precursor in the biosynthesis of coenzyme A, sodium D-
pantothenate is used in the synthesis of coenzyme A. It is also used
in foods as a dietary supplement. | [References]
[1] George A. Burdock, Encyclopedia of Food and Color Additives,
volume 3, 1996 |
| Hazard Information | Back Directory | [Chemical Properties]
White crystal or powder | [Uses]
D-Pantothenic acid sodium (Sodium pantothenate) is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid sodium plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism[1]. | [in vivo]
Pantothenic acid (PTA; 3x10, 3x100, and 3x300 mg/kg) decreases Valproic acid (VPA; 300, 400, and 500 mg/kg, s.c.)-induced neural tube defects in mice[2]. | Animal Model: | Female ICR mice weighing 29-35 g[2] | | Dosage: | 3x10, 3x100, and 3x300 mg/kg (10 mL/kg, volume administered) | | Administration: | Injected intraperitoneally (i.p.) on day 8.5 of gestation | | Result: | Significantly reduced VPA (300, 400, and 500 mg/kg, s.c.)-induced exencephaly, while none of the other external malformations such as open eyelid or skeletal malformations such as fused, absent, or bifurcated ribs and fused thoracic vertebrae and fused sternebrae were reduced. |
| [IC 50]
Human Endogenous Metabolite | [Purification Methods]
Crystallise the salt from absolute EtOH. It is very hygroscopic (keep in sealed ampoules). The free acid is a viscous hygroscopic oil with [] 25D +37.5o (c 5, H2O), easily destroyed by acids and bases. [Beilstein 4 IV 2569.] |
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