| Identification | Back Directory | [Name]
RHODIOSIN | [CAS]
86831-54-1 | [Synonyms]
Rhodiosin
RHODIOSIN; HERBACETIN-7-O-GLUCORHAMNOSIDE
herbacetin 7-O-(3''-O-β-D-glucopyranosyl-α-L-rhamnopyranoside)
7-[(3-O-β-D-Glucopyranosyl-α-L-rhamnopyranosyl)oxy]-3,4',5,8-tetrahydroxyflavone
7-[3-O-(β-D-Glucopyranosyl)-α-L-rhamnopyranosyloxy]-3,5,8-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 7-[(6-deoxy-3-O-β-D-glucopyranosyl-α-L-mannopyranosyl)oxy]-3,5,8-trihydroxy-2-(4-hydroxyphenyl)- | [Molecular Formula]
C27H30O16 | [MDL Number]
MFCD00238673 | [MOL File]
86831-54-1.mol | [Molecular Weight]
610.518 |
| Chemical Properties | Back Directory | [Melting point ]
195-199 °C | [Boiling point ]
994.3±65.0 °C(Predicted) | [density ]
1.82±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Acetone (Slightly, Heated, Sonicated), Methanol (Slightly) | [form ]
Solid | [pka]
6.67±0.40(Predicted) | [color ]
Dark Yellow to Very Dark Yellow | [Stability:]
Hygroscopic | [InChIKey]
WXBBQBYCUTXTJQ-NLLHAXLLNA-N | [SMILES]
O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2[C@H]([C@@H](O[C@H]([C@@H]2O)C)Oc3c(c4[o]c(c([c](c4c(c3)O)=O)O)c5ccc(cc5)O)O)O |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Rhodiola rosea. | [Uses]
Rhodiosin is a flavonol glycoside found in Rhodiola rosea L. with biological activity, and is found in Lishukang capsules, a traditional Chinese medicine. Rhodiosin induces apoptosis in human ovarian cancer OVCAR-?3 cells by activating caspases and Bcl-?2 family proteins. | [in vivo]
Rhodiosin (100 mg/kg, Oral gavage (p.o.), once a day for 10 days) can reduce MDA content in irradiated C57BL mice models and reduce liver damage induced by radiation[4].
| Animal Model: | Irradiation C57BL mice model[4] | | Dosage: | 100 mg/kg, once a day for 10 days | | Administration: | Oral gavage (p.o.) | | Result: | Reduced MDA content in the liver induced by irradiation. |
| [IC 50]
AChE | [storage]
Store at -20°C |
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