| Identification | Back Directory | [Name]
IRISTECTORIGENINA | [CAS]
86849-77-6 | [Synonyms]
Iristetrigenin B
Iristectrigenin B
IRISTECTORIGENINA
4',6-Dimethoxy-3',5,7-trihydroxyisoflavone
6,4'-Dimethoxy-5,7,3'-trihydroxyisoflavone
3-[3-Hydroxy-4-methoxyphenyl]-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one | [Molecular Formula]
C17H14O7 | [MDL Number]
MFCD01662757 | [MOL File]
86849-77-6.mol | [Molecular Weight]
330.29 |
| Chemical Properties | Back Directory | [Boiling point ]
621.2±55.0 °C(Predicted) | [density ]
1.483±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
6.43±0.20(Predicted) | [color ]
Off-white to yellow | [InChI]
InChI=1S/C17H14O7/c1-22-12-4-3-8(5-10(12)18)9-7-24-13-6-11(19)17(23-2)16(21)14(13)15(9)20/h3-7,18-19,21H,1-2H3 | [InChIKey]
WRZOUWHPDDOJNR-UHFFFAOYSA-N | [SMILES]
C1OC2=CC(O)=C(OC)C(O)=C2C(=O)C=1C1=CC=C(OC)C(O)=C1 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Belamcanda chinensis. | [Uses]
Iristectorigenin B (Iristectrigenin B) is a liver X receptor (LXR) modulator. Iristectrigenin B stimulates the transcriptional activity of both LXR-α and LXR-β[1]. | [References]
[1] Hee-jin Jun, et al. Iristectorigenin B isolated from Belamcanda chinensis is a liver X receptor modulator that increases ABCA1 and ABCG1 expression in macrophage RAW 264.7 cells. Biotechnol Lett. 2012 Dec;34(12):2213-21. DOI:10.1007/s10529-012-1036-y |
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