ChemicalBook--->CAS DataBase List--->86923-98-0

86923-98-0

86923-98-0 Structure

86923-98-0 Structure
IdentificationBack Directory
[Name]

BETA-NERVE GROWTH FACTOR, HUMAN
[CAS]

86923-98-0
[Synonyms]

NGFB
hNGFβ
HSAN5
Beta-NGF
MGC161426
MGC161428
RHNGF-BETA
RH-BETA-NGF
NGF-B HUMAN
HUMAN B-NGF
NGF-β human
ProNGF human
NGF-β from rat
HUMAN BETA-NGF
HUMAN NGF-BETA
NGF-BETA HUMAN
BETA-NGF (HUMAN)
HUMAN BETA-NGF PROBE
BETA-TNFRSF 16 (HUMAN)
RECOMBINANT HUMAN B-NGF
BETA-NERVE GROWTH FACTOR
nerve growth factor-β human
HUMAN BETA NERVE GROWTH FACTOR
BETA-NERVE GROWTH FACTOR, HUMAN
NERVE GROWTH FACTOR, BETA-, HUMAN
Mouse beta Nerve growth factor elisa kit
BETA-NERVE GROWTH FACTOR, HUMAN, RECOMBINANT
NERVE GROWTH FACTOR-B, HUMAN*RECOMBINANT , CELL CULT
B-NERVE GROWTH FACTOR, HUMAN RECOMBINANT SYNTHETIC >98%
NGF-β from rat recombinant, expressed in Sf21 cells, lyophilized powder, suitable for cell culture
[MDL Number]

MFCD00164982
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

lyophilized powder
[biological source]

rat
[Water Solubility ]

water: soluble 0.1g/L at20°C
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

NGF-β human has been used:
  • in protein pin arrays
  • to induce U87-MG (glioblastoma cell line) cell proliferation
  • in drug release kinetics

[General Description]

NGFβ (nerve growth factor β) is a protein involved in signal transduction, and expressed by multiple tissues such as placenta, urothelium and bladder smooth muscle cells. It is a neurotrophin and belongs to the NGF family.
[Biochem/physiol Actions]

NGFβ (nerve growth factor β) is essential for the differentiation and survival of neurons. It also plays a key role in the development and maintenance of nervous system. It is also involved in angiogenesis, and facilitates tumorigenesis such as, oral, breast and prostate cancers. It has potential as marker for the diagnosis of interstitial cystitis/painful bladder syndrome (IC/PBS) and overactive bladder (OAB), and might also aid in determining the therapy for the same. It might be involved in changes in placental function, as NGF signaling is influenced by antenatal depression and selective serotonin reuptake inhibitor (SSRI) treatment.
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