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869725-27-9

869725-27-9 Structure

869725-27-9 Structure
IdentificationBack Directory
[Name]

Methanone, (4,6-diMethyl-5-pyriMidinyl)[4-[(3S)-4-[(1R,2R)-2-ethoxy-2,3-dihydro-5-(trifluoroMethyl)-1H-inden-1-yl]-3-Methyl-1-piperazinyl]-4-Methyl-1-piperidinyl]-, (Hydrochloride) (1:2)
[CAS]

869725-27-9
[Synonyms]

INCB009471
INCB-009471
INCB 009471
INCB-9471(HCl)
INCB 9471 HCl,INCB9471 HCl
(4,6-dimethylpyrimidin-5-yl)-[4-[(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl]methanone:dihydrochloride
Methanone, (4,6-diMethyl-5-pyriMidinyl)[4-[(3S)-4-[(1R,2R)-2-ethoxy-2,3-dihydro-5-(trifluoroMethyl)-1H-inden-1-yl]-3-Methyl-1-piperazinyl]-4-Methyl-1-piperidinyl]-, (Hydrochloride) (1:2)
[Molecular Formula]

C30H41ClF3N5O2
[MDL Number]

MFCD18782691
[MOL File]

869725-27-9.mol
[Molecular Weight]

596.14
Hazard InformationBack Directory
[Uses]

CCR5 antagonist 5 (compound example 11) is a CCR5 antagonist. CCR5 antagonist 5 has the potential to study inflammation and immunity and viral (such as HIV) infection[1].
[References]

[1] Discovery of INCB9471, a Potent, Selective, and Orally Bioavailable CCR5 Antagonist with Potent Anti-HIV-1 Activity ACC MCL Publication Date (Web): August 25, 2010 (Letter)
[2] Chu-Biao Xue, et al. Piperazinylpiperidine derivatives as chemokine receptor antagonists. US20050261310A1.
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