Back to ChemicalBook Home--->CAS DataBase List--->869901-69-9

869901-69-9

869901-69-9 Structure

869901-69-9 Structure
IdentificationBack Directory
[Name]

MK-2048
[CAS]

869901-69-9
[Molecular Formula]

C22H24FN5O4
[MOL File]

869901-69-9.mol
[Molecular Weight]

441.455
Chemical PropertiesBack Directory
[density ]

1.55
Hazard InformationBack Directory
[Uses]

MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir (R100312). MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir.
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