| Identification | Back Directory | [Name]
[1,1'-Biphenyl]-4-sulfonamide, 2',4'-difluoro-N-(4-hydroxybutyl)-2-methyl- | [CAS]
871113-99-4 | [Synonyms]
ABD295
ABD-295
ABD 295
ABD295,ABD 295
[1,1'-Biphenyl]-4-sulfonamide, 2',4'-difluoro-N-(4-hydroxybutyl)-2-methyl- | [Molecular Formula]
C17H19F2NO3S | [MOL File]
871113-99-4.mol | [Molecular Weight]
355.4 |
| Hazard Information | Back Directory | [Uses]
ABD-295, a biphenylsulfide derivative, is an antiresorptive agent, osteoclast inhibitor. ABD-295 has potent inhibitory effects on osteoclastic bone resorption in vitro. ABD-295 prevents ovariectomy-induced bone loss in vivo[1]. | [References]
[1] Iain R Greig, et al. Development and characterization of biphenylsulfonamides as novel inhibitors of bone resorption. J Med Chem. 2006 Dec 14;49(25):7487-92. DOI:10.1021/jm051236m |
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