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871113-99-4

871113-99-4 Structure

871113-99-4 Structure
IdentificationBack Directory
[Name]

[1,1'-Biphenyl]-4-sulfonamide, 2',4'-difluoro-N-(4-hydroxybutyl)-2-methyl-
[CAS]

871113-99-4
[Synonyms]

ABD295
ABD-295
ABD 295
ABD295,ABD 295
[1,1'-Biphenyl]-4-sulfonamide, 2',4'-difluoro-N-(4-hydroxybutyl)-2-methyl-
[Molecular Formula]

C17H19F2NO3S
[MOL File]

871113-99-4.mol
[Molecular Weight]

355.4
Chemical PropertiesBack Directory
[Melting point ]

59-61 °C
[Boiling point ]

480.7±55.0 °C(Predicted)
[density ]

1.282±0.06 g/cm3(Predicted)
[pka]

11.15±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

ABD-295, a biphenylsulfide derivative, is an antiresorptive agent, osteoclast inhibitor. ABD-295 has potent inhibitory effects on osteoclastic bone resorption in vitro. ABD-295 prevents ovariectomy-induced bone loss in vivo[1].
[References]

[1] Iain R Greig, et al. Development and characterization of biphenylsulfonamides as novel inhibitors of bone resorption. J Med Chem. 2006 Dec 14;49(25):7487-92. DOI:10.1021/jm051236m
871113-99-4 suppliers list
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871113-99-4