| Identification | Back Directory | [Name]
DLinDMA | [CAS]
871258-12-7 | [Synonyms]
DLinDMA
1,2-Dilinoleyloxy-N,N-dimethyl-3-aminopropane
1-Propanamine, N,N-dimethyl-2,3-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]- | [Molecular Formula]
C41H77NO2 | [MDL Number]
MFCD31715447 | [MOL File]
871258-12-7.mol | [Molecular Weight]
616.06 |
| Chemical Properties | Back Directory | [Boiling point ]
647.8±55.0 °C(Predicted) | [density ]
0.879±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:100.0(Max Conc. mg/mL);162.32(Max Conc. mM)
Ethanol:3.0(Max Conc. mg/mL);4.87(Max Conc. mM) | [form ]
Liquid | [pka]
8.65±0.28(Predicted) | [color ]
Colorless to light yellow | [InChIKey]
NFQBIAXADRDUGK-KWXKLSQISA-N | [SMILES]
C(N(C)C)C(OCCCCCCCC/C=C\C/C=C\CCCCC)COCCCCCCCC/C=C\C/C=C\CCCCC |
| Hazard Information | Back Directory | [Uses]
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery[1]. | [in vivo]
DLinDMA has virtually indistinguishable blood pharmacokinetic profiles in mice[1]. | [References]
[1] Semple SC, et al. Rational design of cationic lipids for siRNA delivery. Nat Biotechnol. 2010 Feb;28(2):172-6. DOI:10.1038/nbt.1602 |
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InvivoChem Gold
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13549236410 |
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https://www.invivochem.cn/ |
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MIDECO Gold
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023-68625073 15723208759 |
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www.midecopharm.com/ |
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