872178-65-9

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872178-65-9 Structure

Identification	Back Directory
[Name] Rob 803
[CAS] 872178-65-9
[Synonyms] Rob 803 RabexiMod Chinfloxacin Hydrochloride 2-(9-chloro-2,3-dimethylindolo[3,2-b]quinoxalin-6-yl)-N-[2-(dimethylamino)ethyl]acetamide 6H-Indolo[2,3-b]quinoxaline-6-acetamide, 9-chloro-N-[2-(dimethylamino)ethyl]-2,3-dimethyl-
[Molecular Formula] C22H24ClN5O
[MDL Number] MFCD18633308
[MOL File] 872178-65-9.mol
[Molecular Weight] 409.91

Hazard Information	Back Directory
[Uses] Rabeximod (ROB-803), an anti-rheumatic compound, impairs the differentiation and function of human pro-inflammatory dendritic cells and macrophages via downregulating TLR2 and TLR4 stimulation. Rabeximod (ROB-803) is used for rheumatoid arthritis (RA) research[1].
[IC 50] TLR2; TLR4
[References] [1] Pablo Giusti, et al. The novel anti-rheumatic compound Rabeximod impairs differentiation and function of human pro-inflammatory dendritic cells and macrophages. Immunobiology. 2011 Jan-Feb;216(1-2):243-50. DOI:10.1016/j.imbio.2010.04.004

Spectrum Detail	Back Directory
[Spectrum Detail] Rob 803(872178-65-9)¹HNMR

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