| Identification | Back Directory | [Name]
GSK 894281 | [CAS]
874958-63-1 | [Synonyms]
GSK894281
GSK-894281
GSK 894281
Benzenesulfonamide, N-[5-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-2-methoxyphenyl]-3-fluoro-4-(5-methyl-2-furanyl)-, rel- | [Molecular Formula]
C24H28FN3O4S | [MOL File]
874958-63-1.mol | [Molecular Weight]
473.56 |
| Hazard Information | Back Directory | [Uses]
GSK894281 is an orally active and highly potent ghrelin receptor full agonist with a pEC50 of <4.9 at the human motilin receptor. GSK894281 effectively enters the CNS. GSK894281 has the potential for constipation or to assist in emptying the colon prior to colonoscopy or colon surgery research[1]. | [References]
[1] A D Shafton, et al.Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation. Neurogastroenterol Motil. 2009 Jan;21(1):71-7. DOI:10.1111/j.1365-2982.2008.01176.x |
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