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876746-59-7

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876746-59-7 Structure

876746-59-7 Structure
IdentificationBack Directory
[Name]

m-PEG3-NHS ester
[CAS]

876746-59-7
[Synonyms]

mPEG2-SPA
m-PEG3-NHS ester
mPEG2-CH2CH2COONHS
mPEG2-CH2CH2COONHS Ester
2,5-Dioxopyrrolidin-1-yl 3-(2-(2-methoxyethoxy)ethoxy)propanoate
[Molecular Formula]

C12H19NO7
[MDL Number]

MFCD20228789
[MOL File]

876746-59-7.mol
[Molecular Weight]

289.28
Chemical PropertiesBack Directory
[Boiling point ]

393.7±50.0 °C(Predicted)
[density ]

1.25±0.1 g/cm3(Predicted)
[solubility ]

Soluble in DMSO, DCM, DMF
Hazard InformationBack Directory
[Description]

m-PEG3-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses]

m-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
[References]

[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74
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