| Identification | Back Directory | [Name]
6-Hydroxyrubiadin | [CAS]
87686-86-0 | [Synonyms]
6-Hydroxyrubiadin
9,10-Anthracenedione, 1,3,6-trihydroxy-2-methyl- | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C15H10O5 | [MDL Number]
MFCD18448218 | [MOL File]
87686-86-0.mol | [Molecular Weight]
270.24 |
| Hazard Information | Back Directory | [Uses]
6-Hydroxyrubiadin, a natural anthraquinone, may be a potential therapeutic candidate for the treatment of inflammation and inflammatory diseases[1]. | [Definition]
ChEBI: A trihydroxyanthraquinone that is 9,10-anthraquinone substituted by hydroxy groups at positions 1, 3 and 6 and a methyl group at position 2. It has been isolated from the roots of Rubia yunnanensis. | [in vivo]
6-hydroxyrubiadin can reduce the production of pro-inflammatory cytokines and ameliorate acute lung injury (ALI) in a mouse model[1]. | [References]
[1] Yanting Wu, et al. In vitro and in vivo inhibitory effects of 6-hydroxyrubiadin on lipopolysaccharide-induced inflammation. Immunopharmacol Immunotoxicol. 2017 Jun;39(3):107-116. DOI:10.1080/08923973.2017.1295053 |
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