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877674-77-6

877674-77-6 Structure

877674-77-6 Structure
IdentificationBack Directory
[Name]

7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid
[CAS]

877674-77-6
[Synonyms]

Cilastatin Impurity
Cilastatin Impurity 1
Cilastatin Impurity 14
(+)-(Z)-7-CHLORO-2-【2,2-DIMETHYLCYCLOPROPANECARBOXA MIDO】-2-HEPTENOIC ACID
7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid
(E)-7-chloro-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid
(2Z)-7-chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-Heptenoic acid
2-Heptenoic acid, 7-chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-, (2Z)-
[EINECS(EC#)]

618-065-4
[Molecular Formula]

C13H20ClNO3
[MDL Number]

MFCD19440921
[MOL File]

877674-77-6.mol
[Molecular Weight]

273.76
Questions And AnswerBack Directory
[Uses]

(2Z)​-7-​Chloro-​2-​[[[(1S)​-​2,​2-​dimethylcyclopropyl]​carbonyl]​amino]​-​2-​heptenoic Acid is a reagent used in the preparation of Cilastatin (C441105), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
Chemical PropertiesBack Directory
[Melting point ]

93-97oC
[Boiling point ]

504.5±50.0 °C(Predicted)
[density ]

1.189
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

4.11±0.19(Predicted)
[color ]

White to Off-White
[Stability:]

Hygroscopic
[LogP]

3.2
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H317
[Precautionary statements ]

P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
[REACH Registrations]

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