ChemicalBook--->CAS DataBase List--->878557-19-8

878557-19-8

878557-19-8 Structure

878557-19-8 Structure
IdentificationBack Directory
[Name]

23-(dipyrroMetheneboron difluoride)-24-norcholesterol
[CAS]

878557-19-8
[Synonyms]

BCh2
BODIPY-Cholesterol
TopFluor Cholesterol
BODIPY-Cholesterol (BCh2)
BODIPY 480/508-Cholesterol
23-(dipyrroMetheneboron difluoride)-24-norcholesterol
23-(DIPYRROMETHENEBORON DIFLUORIDE)-24-NORCHOLESTEROL;TOPFLUOR CHOLESTEROL
[(3β)-24-(3,5-Dimethyl-1H-pyrrol-2-yl-κN)-24-(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)chol-5-en-3-olato]difluoroboron
[Molecular Formula]

C36H51BF2N2O
[MDL Number]

MFCD22416769
[MOL File]

878557-19-8.mol
[Molecular Weight]

576.611
Chemical PropertiesBack Directory
[storage temp. ]

Amber Vial, -20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform (Slightly)
[form ]

Solid
[color ]

Red
[Appearance]

Red Solid
[InChIKey]

CFFWELDLDWZNRO-ZVEUZXBYSA-N
[SMILES]

C1C[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@]([H])([C@H](C)CCC5=C6C(C)=CC(C)=[N+]6[B-](F)(F)N6C(C)=CC(C)=C56)CC[C@@]4([H])[C@]3([H])CC=C2C[C@H]1O
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Description]

BODIPY-cholesterol is a cell-permeable analog of cholesterol that is tagged with BODIPY group. BODIPY-cholesterol mimics the membrane partitioning and trafficking of cholesterol, and it is often used to study the sterol distribution and transport in living cells.

[Uses]

TopFluor Cholesterol forms a complex with other lipid molecules during its macroscopic diffusion in giant unilamellar vesicles (GUVs) lipid bilayers at room temperature. It is also a new cholesterol probe with superior fluorescence properties. TopFluor Cholesterol is the derivative of Cholesterol (C432501), which is the principal sterol of the higher animals and found in all body tissues, especially in the brain, spinal cord, and in animal fats and oil.
[Biological Activity]

BODIPY labelled cholesterol has similar properties to th at of the na?ve cholesterol. This serves as a cholesterol marker for live cells and aids in trafficking intracellular cholesterol. It might also help in indicating lipid storage diseases.
[Excitation / Emission Maximum]

480 nm/508 nm
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