| Identification | Back Directory | [Name]
6-BROMO-3-IODO (1H)INDAZOLE | [CAS]
885521-88-0 | [Synonyms]
3-Iodo-6-BroMoindazole
6-Bromo-3-iodo-1H-indazoL
6-BROMO-3-IODO (1H)INDAZOLE
1H-INDAZOLE, 6-BROMO-3-IODO- | [Molecular Formula]
C7H4BrIN2 | [MDL Number]
MFCD07781599 | [MOL File]
885521-88-0.mol | [Molecular Weight]
322.93 |
| Chemical Properties | Back Directory | [Boiling point ]
413.1±25.0 °C(Predicted) | [density ]
2.421 | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [pka]
10.82±0.40(Predicted) | [Appearance]
White to yellow Solid | [InChI]
InChI=1S/C7H4BrIN2/c8-4-1-2-5-6(3-4)10-11-7(5)9/h1-3H,(H,10,11) | [InChIKey]
POXUFQBYDQCUFO-UHFFFAOYSA-N | [SMILES]
N1C2=C(C=CC(Br)=C2)C(I)=N1 | [CAS DataBase Reference]
885521-88-0 |
| Hazard Information | Back Directory | [Application]
A new and efficient Pd/C mediated method for C-3 alkynylation of 1H indazoles. 6-Bromo-3-iodo-1H-indazole was coupled with terminal alkynes in presence of Pd/ C-CuI-PPh3 catalytic system in ethanol solvent at 70°C to afford C-3 alkynylated products and/or C-3/C-6 dialkynylated products with good to excellent yields.1 | [References]
[1] Ghosh, S., Mondal, S., & Hajra, A. (2020). Direct Catalytic Functionalization of Indazole Derivatives. <i>Advanced Synthesis &amp; Catalysis, 362 18, Pages 3768-3794. https://doi.org/10.1002/adsc.202000423
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