| Identification | Back Directory | [Name]
H-Ala-Cys-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys-Gly-OH, (Disulfide bond) | [CAS]
888486-23-5 | [Synonyms]
TD 1 (peptide)
Transdermal Peptide Disulfide
Transdermal Peptide (TD 1 peptide)
H-Ala-Cys-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys-Gly-OH, (Disulfide bond)
Glycine, L-alanyl-L-cysteinyl-L-seryl-L-seryl-L-seryl-L-prolyl-L-seryl-L-lysyl-L-histidyl-L-cysteinyl-, cyclic (2→10)-disulfide (9CI) | [Molecular Formula]
C40H64N14O16S2 | [MDL Number]
MFCD32263454 | [MOL File]
888486-23-5.mol | [Molecular Weight]
1061.15 |
| Chemical Properties | Back Directory | [Boiling point ]
1728.7±65.0 °C(Predicted) | [density ]
1.54±0.1 g/cm3(Predicted) | [pka]
3.57±0.10(Predicted) | [Sequence]
H-Ala-Cys-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys-Gly-OH(Disulfide bond) |
| Hazard Information | Back Directory | [Uses]
Transdermal Peptide Disulfide (TD 1 Disulfide(peptide)) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide Disulfide can enhance the transdermal delivery of many macromolecules[1]. | [References]
[1] Wang C, et al. Role of the Na(+)/K(+)-ATPase beta-subunit in peptide-mediated transdermal drug delivery. Mol Pharm. 2015 Apr 6;12(4):1259-67. DOI:10.1021/mp500789h |
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