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88901-36-4

88901-36-4 Structure

88901-36-4 Structure
IdentificationBack Directory
[Name]

Mogroside V
[CAS]

88901-36-4
[Synonyms]

groside V
Rohypnol V
Mogroside Ⅴ
Mogroside V
Mogrosides V
MOGROSIDE V(P)
mogrosides,Mog
Luo Han Guo P.E.
Mogroside V ,98%
Luo Han Guo PE80%
Momordica Extract
Momordica saponin V
Monk fruite extract
Monkfruit Sweetener
Mogroside V (100 mg)
Mogroside V Standard
Momordica grosvenori
Mogroside V USP/EP/BP
Mangosteen Sweet Pork
Wood turtle seed extract
Momordica grosvenori swingle
Grosvenor MoMordica Glucoside
MomordicagrosvenoriSwingleP.E
Siraitia grosvenorii saponin V
Luo Han Guo(Lo Han Guo) Extract
Momordica cochinchinensis extract
Mogroside V, froM Fructus MoMordicae
Momordica Grosvenori Extract Mogroside V
Mogroside V, 98%, from Fructus Momordicae
Mogroside V, 98%, from Siraitia grosvenorii (Swingle)
(24R)-3β-[6-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-24-[2-O,6-O-bis(β-D-glucopyranosyl)-β-D-glucopyranosyloxy]cucurbit-5-ene-11α,25-diol
Mogrol-3-o-(beta-D-glucopyranosyl (1-6)-beta-D-glucopyranoside)-24-o-((beta-D-glucopyranosyl (1-2))-(beta-D-glucopyranosyl(1-6))-beta-D-glucopyranoside)
β-D-Glucopyranoside, (3β,9β,10α,11α,24R)-3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-11,25-dihydroxy-9-methyl-19-norlanost-5-en-24-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→6)]-
beta-D-Glucopyranoside, (3beta,9beta,10alpha,11alpha,24R)-3-((6-o-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-11,25-dihydroxy-9-methyl-19-norlanost-5-en-24-yl o-beta-D-glucopyranosyl-(1-2)-o-(beta-D-glucopyranosyl-(1-6))-
(2S,3R,4S,5S,6R)-2-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-2-(((3R,6R)-2-hydroxy-6-((3S,8S,9R,10R,11R,13R,14S,17R)-11-hydroxy-4,4,9,13,14-pentamethyl-3-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptan-3-yl)oxy)-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)m
[EINECS(EC#)]

695-005-3
[Molecular Formula]

C60H102O29
[MDL Number]

MFCD00238649
[MOL File]

88901-36-4.mol
[Molecular Weight]

1287.44
Chemical PropertiesBack Directory
[Melting point ]

197~201℃
[density ]

1.51
[storage temp. ]

2-8°C
[solubility ]

Methanol (Slightly, Sonicated), Pyrindine (Slightly), Water (Slightly)
[form ]

Solid
[pka]

12.82±0.70(Predicted)
[color ]

White to Off-White
[Stability:]

Hygroscopic
[Major Application]

pharmaceutical (small molecule)
[InChIKey]

GHBNZZJYBXQAHG-REURRCPBNA-N
[LogP]

-1.069 (est)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
[Safety Statements ]

24/25
[WGK Germany ]

WGK 3
[HS Code ]

29389090
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Chemical Properties]

White powder
[Uses]

Mogroside V is used as a natural sweetener. Existing as a triterpenoidal saponina from the fruit of Siraitia grosvenorii Swingle, mogrosides are often used as a substitute for sugar by the food industry. Also acts as a potential anti-inflammatory for the lung airway.
[General Description]

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG.
[Synthesis]

The biosynthesis of Mogroside V involves five enzyme families: squalene epoxidases, triterpenoid synthases, epoxide hydrolases, cytochrome P450s, and UDP-glucosyltransferases. Specifically, the uridine diphosphate-dependent glycosyltransferases UGT720-269-1 and UGT94-289-3 from S. grosvenorii catalyze the glycosylation of mogrol in vitro to produce Mogroside V[1][2].
[target]

AMPK | Immunology & Inflammation related
[References]

[1]Itkin, M., Davidovich-Rikanati, R., Cohen, S., Portnoy, V., Doron-Faigenboim, A., Oren, E., Freilich, S., Tzuri, G., Baranes, N., Shen, S., Petreikov, M., Sertchook, R., Ben-Dor, S., Gottlieb, H., Hernandez, A., Nelson, D. R., Paris, H. S., Tadmor, Y., Burger, Y., … Schaffer, A. (2016). The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V from <i>Siraitia grosvenorii</i>. Proceedings of the National Academy of Sciences, 113(47). https://doi.org/10.1073/pnas.1604828113
[2]Qu, G., Song, Y., Xu, X., Liu, Y., Li, J., Du, G., Liu, L., Li, Y., & Lv, X. (2025). De novo biosynthesis of mogroside V by multiplexed engineered yeasts. Metabolic Engineering, 88, 160–171. https://doi.org/10.1016/j.ymben.2025.01.002
Spectrum DetailBack Directory
[Spectrum Detail]

Mogroside V(88901-36-4)1HNMR
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