| Identification | Back Directory | [Name]
Mogroside V | [CAS]
88901-36-4 | [Synonyms]
groside V Rohypnol V Mogroside Ⅴ Mogroside V Mogrosides V MOGROSIDE V(P) mogrosides,Mog Luo Han Guo P.E. Mogroside V ,98% Luo Han Guo PE80% Momordica Extract Momordica saponin V Monk fruite extract Monkfruit Sweetener Mogroside V (100 mg) Mogroside V Standard Momordica grosvenori Mogroside V USP/EP/BP Mangosteen Sweet Pork Wood turtle seed extract Momordica grosvenori swingle Grosvenor MoMordica Glucoside MomordicagrosvenoriSwingleP.E Siraitia grosvenorii saponin V Luo Han Guo(Lo Han Guo) Extract Momordica cochinchinensis extract Mogroside V, froM Fructus MoMordicae Momordica Grosvenori Extract Mogroside V Mogroside V, 98%, from Fructus Momordicae Mogroside V, 98%, from Siraitia grosvenorii (Swingle) (24R)-3β-[6-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-24-[2-O,6-O-bis(β-D-glucopyranosyl)-β-D-glucopyranosyloxy]cucurbit-5-ene-11α,25-diol Mogrol-3-o-(beta-D-glucopyranosyl (1-6)-beta-D-glucopyranoside)-24-o-((beta-D-glucopyranosyl (1-2))-(beta-D-glucopyranosyl(1-6))-beta-D-glucopyranoside) β-D-Glucopyranoside, (3β,9β,10α,11α,24R)-3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-11,25-dihydroxy-9-methyl-19-norlanost-5-en-24-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→6)]- beta-D-Glucopyranoside, (3beta,9beta,10alpha,11alpha,24R)-3-((6-o-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-11,25-dihydroxy-9-methyl-19-norlanost-5-en-24-yl o-beta-D-glucopyranosyl-(1-2)-o-(beta-D-glucopyranosyl-(1-6))- (2S,3R,4S,5S,6R)-2-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-2-(((3R,6R)-2-hydroxy-6-((3S,8S,9R,10R,11R,13R,14S,17R)-11-hydroxy-4,4,9,13,14-pentamethyl-3-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptan-3-yl)oxy)-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)m | [EINECS(EC#)]
695-005-3 | [Molecular Formula]
C60H102O29 | [MDL Number]
MFCD00238649 | [MOL File]
88901-36-4.mol | [Molecular Weight]
1287.44 |
| Chemical Properties | Back Directory | [Melting point ]
197~201℃ | [density ]
1.51 | [storage temp. ]
2-8°C | [solubility ]
Methanol (Slightly, Sonicated), Pyrindine (Slightly), Water (Slightly) | [form ]
Solid | [pka]
12.82±0.70(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic | [Major Application]
pharmaceutical (small molecule) | [InChIKey]
GHBNZZJYBXQAHG-REURRCPBNA-N | [LogP]
-1.069 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
Mogroside V is used as a natural sweetener. Existing as a triterpenoidal saponina from the fruit of Siraitia grosvenorii Swingle, mogrosides are often used as a substitute for sugar by the food industry. Also acts as a potential anti-inflammatory for the lung airway. | [General Description]
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG. | [Synthesis]
The biosynthesis of Mogroside V involves five enzyme families: squalene epoxidases, triterpenoid synthases, epoxide hydrolases, cytochrome P450s, and UDP-glucosyltransferases. Specifically, the uridine diphosphate-dependent glycosyltransferases UGT720-269-1 and UGT94-289-3 from S. grosvenorii catalyze the glycosylation of mogrol in vitro to produce Mogroside V[1][2]. | [target]
AMPK | Immunology & Inflammation related | [References]
[1]Itkin, M., Davidovich-Rikanati, R., Cohen, S., Portnoy, V., Doron-Faigenboim, A., Oren, E., Freilich, S., Tzuri, G., Baranes, N., Shen, S., Petreikov, M., Sertchook, R., Ben-Dor, S., Gottlieb, H., Hernandez, A., Nelson, D. R., Paris, H. S., Tadmor, Y., Burger, Y., … Schaffer, A. (2016). The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V from <i>Siraitia grosvenorii</i>. Proceedings of the National Academy of Sciences, 113(47). https://doi.org/10.1073/pnas.1604828113 [2]Qu, G., Song, Y., Xu, X., Liu, Y., Li, J., Du, G., Liu, L., Li, Y., & Lv, X. (2025). De novo biosynthesis of mogroside V by multiplexed engineered yeasts. Metabolic Engineering, 88, 160–171. https://doi.org/10.1016/j.ymben.2025.01.002 |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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