| Identification | Back Directory | [Name]
8(S)-HETRE | [CAS]
889573-69-7 | [Synonyms]
8(S)-HETRE
SKIQVURLERJJCK-RDCCVJQZSA-N
8S-HYDROXY-9E,11Z,14Z-EICOSATRIENOIC ACID | [Molecular Formula]
C20H34O3 | [MDL Number]
MFCD00216111 | [MOL File]
889573-69-7.mol | [Molecular Weight]
322.48 |
| Chemical Properties | Back Directory | [Boiling point ]
459.0±45.0 °C(Predicted) | [density ]
0.971±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml | [pka]
4.77±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
8(S)-HETrE is a monohydroxy polyunsaturated fatty acid produced by rabbit neutrophil lipoxygenase when dihomo-γ-linolenic acid (DGLA; ) is used as a substrate. Although the biological activities of 8(S)-HETrE have not been well characterized, it is expected to behave similarly to 8(S)-HETE . | [Uses]
(S,9E,11Z,14Z)-8-Hydroxyicosa-9,11,14-trienoic acid is an ester product. | [Definition]
ChEBI: 8(S)-HETrE is an 8-HETrE. | [References]
[1] DU Y, XIANG DING-LI, YU DONG-LU, et al. Lipid metabolism disorders and lipid mediator changes of mice in response to long-term exposure to high-fat and high sucrose diets and ameliorative effects of mulberry leaves?[J]. Food & Function, 2022, 8: 4576-4591. DOI: 10.1039/d1fo04146k |
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