ChemicalBook--->CAS DataBase List--->889665-86-5

889665-86-5

889665-86-5 Structure

889665-86-5 Structure
IdentificationBack Directory
[Name]

Epiberberine (chloride)
[CAS]

889665-86-5
[Synonyms]

Epiberberine chloride, 99.5%
[Molecular Formula]

C20H18ClNO4
[MDL Number]

MFCD01549686
[MOL File]

889665-86-5.mol
[Molecular Weight]

371.82
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO:25.0(Max Conc. mg/mL);67.24(Max Conc. mM)
[form ]

Solid
[color ]

Orange to Very Dark Orange
[Stability:]

Light Sensitive
Hazard InformationBack Directory
[Uses]

Epiberberine Chloride, is a natural bioactive alkaloid, an isomer of Berberine (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells.
[in vivo]

Epiberberine (225 mg/kg, p.o. daily for 40 days) reduces body weight, food consumption, water intake, and urinary output of KK-Ay mice[3].

[IC 50]

AChE; BACE1; BChE
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