ChemicalBook--->CAS DataBase List--->89430-34-2

89430-34-2

89430-34-2 Structure

89430-34-2 Structure
IdentificationBack Directory
[Name]

D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-NLE-NH2
[CAS]

89430-34-2
[Synonyms]

Pttnl-sp(4-11)
4-Pro-7,9-Trp-11-nle-substance p (4-11)
D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-NLE-NH2
(D-PRO4,D-TRP7,9,NLE11)-SUBSTANCE P (4-11)
H-D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-NLE-NH2
substance P (4-11), Pro(4)-Trp(7,9)-Nle(11)-
(D-pro4,D-trp7,9,nle11)-substance P*fragment 4-11
SUBSTANCE P [D-PRO4,D-TRP7,9,NLE11]-FRAGMENT 4-11
D-Pro-L-Gln-L-Gln-D-Trp-L-Phe-D-Trp-L-Leu-L-Nle-NH2
Substance P, fragment 4-11, [D-Pro4, D-Trp7,9, Nle11]
4-Prolyl-7,9-tryptophyl-11-norleucine-substance p (4-11)
Substance p (4-11), prolyl (4)-tryptophyl(7,9)-norleucine(11)-
L-Norleucinamide, D-prolyl-L-glutaminyl-L-glutaminyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-L-leucyl-
[Molecular Formula]

C58H77N13O10
[MDL Number]

MFCD00133834
[MOL File]

89430-34-2.mol
[Molecular Weight]

1116.31
Chemical PropertiesBack Directory
[Boiling point ]

1587.9±65.0 °C(Predicted)
[density ]

1.286±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[pka]

13.27±0.46(Predicted)
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP)[1].
[References]

[1] Cathieni M M, et al. Pharmacological Evidence that Gold-Protein-Substance P Complex Activates Neurokinin NK1 Receptors[J]. Cellular Physiology & Biochemistry, 1995, 5(2):85-95.
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