| Identification | Back Directory | [Name]
HELODERMIN | [CAS]
89468-62-2 | [Synonyms]
Exendin 2
HELODERMIN
HELODORMIN
heliodermin
VIP-PHI LIKE PEPTIDE
HELODERMIN (HELODERMA SUSPECTUM)
HSDAIFTQQYSKLLAKLALQKYLASILGSRTSPPP
HSDAIFTGEYSKLLAKLALQKYLASILGSRTSPPP-NH2
VASOACTIVE INTESTINAL PEPTIDE-PHI LIKE PEPTIDE
H-HIS-SER-ASP-ALA-ILE-PHE-THR-GLU-GLU-TYR-SER-LYS-LEU-LEU-ALA-LYS-ALA-LEU-GLN-LYS-TYR-LEU-ALA-SER-ILE-LEU-GLY-SER-ARG-THR-SER-PRO-PRO-PRO-NH2
HIS-SER-ASP-ALA-ILE-PHE-THR-GLN-GLN-TYR-SER-LYS-LEU-LEU-ALA-LYS-LEU-ALA-LEU-GLN-LYS-TYR-LEU-ALA-SER-ILE-LEU-GLY-SER-ARG-THR-SER-PRO-PRO-PRO-NH2
HIS-SER-ASP-ALA-ILE-PHE-THR-GLU-GLU-TYR-SER-LYS-LEU-LEU-ALA-LYS-LEU-ALA-LEU-GLN-LYS-TYR-LEU-ALA-SER-ILE-LEU-GLY-SER-ARG-THR-SER-PRO-PRO-PRO-NH2
H-HIS-SER-ASP-ALA-ILE-PHE-THR-GLN-GLN-TYR-SER-LYS-LEU-LEU-ALA-LYS-LEU-ALA-LEU-GLN-LYS-TYR-LEU-ALA-SER-ILE-LEU-GLY-SER-ARG-THR-SER-PRO-PRO-PRO-NH2
H-His-Ser-Asp-Ala-Ile-Phe-Thr-Glu-Glu-Tyr-Ser-Lys-Leu-Leu-Ala-Lys-Leu-Ala-Leu-Gln-Lys-Tyr-Leu-Ala-Ser-Ile-Leu-Gly-Ser-Arg-Thr-Ser-Pro-Pro-Pro-NH2 | [Molecular Formula]
C176H285N47O49 | [MDL Number]
MFCD08062321 | [MOL File]
89468-62-2.mol | [Molecular Weight]
3843.43 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [form ]
ethanol solution | [Sequence]
His-Ser-Asp-Ala-Ile-Phe-Thr-Gln-Gln-Tyr-Ser-Lys-Leu-Leu-Ala-Lys-Leu-Ala-Leu-Gln-Lys-Tyr-Leu-Ala-Ser-Ile-Leu-Gly-Ser-Arg-Thr-Ser-Pro-Pro-Pro-NH2 |
| Hazard Information | Back Directory | [Uses]
Helodormin is a VIP-secretin-like peptide isolated from the venom of the Mexican monster lizard (Heloderma suspectum). Helodormin affects a variety of cellular functions by modulating intracellular signaling through activation of adenylate cyclase. Helodormin can be used to study the evolution and function of the secretin and VIP peptide families[1]. | [References]
[1] Hoshino M, et al. Primary structure of helodermin, a VIP-secretin-like peptide isolated from Gila monster venom[J]. FEBS letters, 1984, 178(2): 233-239. DOI:10.1016/0014-5793(84)80607-9 |
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