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895470-67-4

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895470-67-4 Structure

895470-67-4 Structure
IdentificationBack Directory
[Name]

Cardioprotectant
[CAS]

895470-67-4
[Synonyms]

CP312
CP-312
CP 312
Cardioprotectant
Cardioprotectant 312
[Molecular Formula]

C16H12ClN3OS2
[MOL File]

895470-67-4.mol
[Molecular Weight]

361.87
Chemical PropertiesBack Directory
[density ]

1.45±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

7.68±0.50(Predicted)
[color ]

Off-white to pink
Hazard InformationBack Directory
[Description]

CP-312 is an activator of the antioxidant defense response. It acts by inducing heme oxygenase-1 and protecting human iPSC-derived cardiomyocytes from oxidative stress.
[Uses]

CP-312 is a potent Heme Oxygenase-1 (HO-1) inducer. CP-312 protects hiPSC-CM viability by targeting the antioxidant response network through induction of HMOX1 expression. CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress[1].
[References]

[1] Kirby RJ, et, al. Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress. J Pharmacol Exp Ther. 2018 Jan;364(1):87-96. DOI:10.1124/jpet.117.243717
Spectrum DetailBack Directory
[Spectrum Detail]

Cardioprotectant(895470-67-4)1HNMR
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