| Identification | Back Directory | [Name]
(3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid | [CAS]
89913-60-0 | [Synonyms]
α-acetyl Boswellic Acid
Acetyl-α-boswellic Acid
α-Boswellic acid acetate
3-Acetyl-α-boswellic acid
Boswellic Acid Impurity 1
Acetyl-alpha-boswellic acid
3-O-Acetyl-α-boswellic acid
alpha-Boswellic acid acetate
3-O-Acetyl-alpha-boswellic acid
3α-(Acetyloxy)olean-12-en-24-oic acid
(3α,4β)-3-(Acetyloxy)olean-12-en-23-oic acid
Olean-12-en-23-oic acid, 3-(acetyloxy)-, (3α,4β)-
Olean-12-en-23-oic acid, 3-(acetyloxy)-, (3α,4β)-
(3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid
(3R,4R,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-3-acetyloxy-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4-carboxylic acid | [Molecular Formula]
C32H50O4 | [MDL Number]
MFCD03788772 | [MOL File]
89913-60-0.mol | [Molecular Weight]
498.74 |
| Chemical Properties | Back Directory | [Melting point ]
230-232℃ | [Boiling point ]
563.6±50.0 °C(Predicted) | [density ]
1.10 | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly) | [form ]
neat | [pka]
4.32±0.70(Predicted) | [color ]
White to Off-White | [LogP]
10.320 (est) |
| Hazard Information | Back Directory | [Description]
α-acetyl Boswellic acid is a pentacyclic triterpene and isomer of β-acetyl-boswellic acid originally isolated from B. serrata. It inhibits LPS-induced TNF-α mRNA expression in monocytes as well as NF-κB activity in HEK293 cells when used at a concentration of 10 μM. α-acetyl Boswellic acid also inhibits phosphorylation of IκBα mediated by IκB kinases (IKKs) in monocytes. | [Uses]
Acetyl-α-boswellic Acid is a selective inhibitor of COX-1. It also inhibits NF-KB signaling in LPS-stimulated monocytes. | [Definition]
ChEBI: 3-alpha-O-acetyl-alpha-boswellic acid is a triterpenoid. It has a role as a metabolite. | [target]
PGE | [storage]
4°C, away from moisture and light | [References]
[1] TATIANA SYROVETS. Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-alpha induction in monocytes by direct interaction with IkappaB kinases.[J]. Journal of immunology, 2005, 174 1: 498-506. DOI: 10.4049/jimmunol.174.1.498 |
|
| Company Name: |
WG reagent
|
| Telephone: |
13391486464 |
| Website: |
www.wgchemical.com |
|