| Identification | Back Directory | [Name]
(-)-SPARTEINE | [CAS]
90-39-1 | [Synonyms]
Spartein
Spartine
eulexine
SPARTEINE
Lupinidin
LUPINIDINE
Lupinindin
1-Sparteine
(-)-spartein
(-)-SPARTEINE
SPARTEINE(RG)
(-)-LUPINIDINE
L-(-)-SPARTEINE
(-)-Sparteine,99%
Sparteine (6CI,8CI)
(-)-Sparteine H2SO4
(−)-Sparteine
1',2'-e][1,5]diazocine
Sparteine (CAS:6160-12-9)
6β,7α,9α,11α-Pachycarpine
MINUS-SPARTEINE FREE BASE
6beta,7alpha,9alpha,11alpha-Pachycarpine
6-beta,7-alpha,9-alpha,11-alpha-pachycarpine
6h-dipyrido(1,2-a:1’,2’-e)(1,5)diazocine,dodecahydro-14-methano-2h
7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-
(-)-Lupinidine, (7S,&aR,14S,14aS)-Dodecahydro-7,14-methano-dipyrido[1,2-a
(7S,7aα,14α,14aβ)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine,dodecahydro-, (7S,7aR,14S,14aS)-
Dodecahydro [7S-(7alpha,7aalpha,14alpha,14abeta)]-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, [7S-(7alpha,7aalpha,14alpha,14abeta)]- | [EINECS(EC#)]
201-988-8 | [Molecular Formula]
C15H26N2 | [MDL Number]
MFCD00069653 | [MOL File]
90-39-1.mol | [Molecular Weight]
234.38 |
| Chemical Properties | Back Directory | [Melting point ]
30.5°C | [alpha ]
D21 -16.4° (c = 10 in abs alc) | [Boiling point ]
137-138 °C1 mm Hg(lit.)
| [density ]
1.02 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.528(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly), Ethanol (Slightly) | [form ]
liquid | [pka]
2.24, 9.46(at 20℃) | [color ]
Light Yellow to Yellow | [Optical Rotation]
[α]/D -17.5±1.5°, c = 1 in ethanol | [Water Solubility ]
3.04g/L(25 ºC) | [Merck ]
14,8737 | [BRN ]
82447 | [InChI]
1S/C15H26N2/c1-3-7-16-11-13-9-12(14(16)5-1)10-17-8-4-2-6-15(13)17/h12-15H,1-11H2/t12-,13-,14-,15+/m0/s1 | [InChIKey]
SLRCCWJSBJZJBV-ZQDZILKHSA-N | [SMILES]
C1CCN2C[C@@H]3C[C@@H](CN4CCCC[C@H]34)[C@@H]2C1 | [LogP]
3.210 (est) |
| Hazard Information | Back Directory | [Description]
Sparteine is effective against sinoatrial and
atrial tachycardias, atrial extrasystoles, and also
against ventricular arrhythmias . Despite
prolongation of the myocardial refractory period
in vitro, theECGtimes are not prolonged in vivo. | [Chemical Properties]
Viscous oily liquid; boils around 180°C(356°F); density 1.02 at 20°C (68°F); stronglybasic, a 0.01 M soln. has pH 11.6; slightlysoluble in water (0.3 g/100 mL), dissolvesreadily in alcohol, ether, or chloroform. | [Uses]
Sparteine occurs in yellow and black lupinbeans (Lupinus luteus L. and L. niger). Italso occurs in other Lupinus species aswell as in Cytisus and Spartium species.Therapeutically, it is used as an oxytocicagent. | [Definition]
ChEBI: Sparteine is a quinolizidine alkaloid and a quinolizidine alkaloid fundamental parent. | [Health Hazard]
Toxic actions of sparteine are similar to thoseof coniine but are much less toxic than thoseof coniine. The toxic symptoms in mice weretremor, muscle contraction, and respiratorydistress. An intraperitoneal dose lethal toguinea pigs is 23 mg/kg.
LD50 value, oral (mice): 220 mg/kg. |
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