ChemicalBook--->CAS DataBase List--->9001-45-0

9001-45-0

9001-45-0 Structure

9001-45-0 Structure
IdentificationBack Directory
[Name]

EC 3.2.1.31
[CAS]

9001-45-0
[Synonyms]

KETODASE
glucurase
EC 3.2.1.31
EC: 3.2.1.31
B-GLUCURONIDASE
beta-glucuronidas
BETA-GLUCURONIDASE
beta-d-glucuronidase
B-glucuronidase type B-3
B-glucuronidase type B-I
β-Glucuronidase–Agarose.
B-glucuronidase type B-10
BETA-GLUCURONIDASE TYPE X-A
BETA-GLUCURONIDASE TYPE B-3
BETA-GLUCURONIDASE TYPE H-1
BETA-GLUCURONIDASE TYPE H-2
BETA-GLUCURONIDASE TYPE H-3
BETA-GLUCURONIDASE TYPE H-5
BETA-GLUCURONIDASE TYPE B-1
BETA-GLUCURONIDASE TYPE B-10
BETA-GLUCURONIDASE TYPE IX-A
BETA-GLUCURONIDASE TYPE L-II
BETA-GLUCURONIDASE TYPE HA-4
BETA-GLUCURONIDASE TYPE HP-2
β-Glucuronidase from E. coli
β-Glucuronidase from abalone
BETA-GLUCURONIDASE TYPE HP-2S
BETA-GLUCURONIDASE TYPE VII-A
BETA-GLUCURONIDASE TYPE H-3AF
BETA-GLUCURONIDASE, BACTERIAL
BETA-GLUCURONIDASE, LYMPHOCYTE
beta-glucuronidase E. coli K12
BETA-GLUCURONIDASE RECOMBINANT
B-GLUCURONIDASE PREWEIGHED VIALS
Beta-GlucuronidaseExMarineMollusc
β-glucuronidase from bovine liver
β-glucuronidase from helix pomatia
beta-glucuronideglucuronohydrolase
beta-Glucuronidase Escherichia coli
beta-Glucuronidase from E. coli K12
beta-Glucuronidase from bovine liver
β-d-glucuronide glucuronosohydrolase
β-Glucuronidase from E. coli K12
β-glucuronidase from escherichia coli
beta-glucuronidase from helix pomatia
B-glucuronidase from abalone entrails
B-GLUCURONIDASE TYPE X-A FROM E. COLI
BETA-GLUCURONIDASE E. COLI K12 STAB.
B-GLUCURONIDASE TYPE S-I FROM SCALLOPS
B-GLUCURONIDASE TYPE L-II FROM LIMPETS
B-GLUCURONIDASE TYPE IX-A FROM E. COLI
B-GLUCURONIDASE TYPE VII-A FROM E. COLI
B-glucuronidase from mollusk type H-3af
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE
BETA-GLUCURONIDASE FROM E. COLI &
B-GLUCURONIDASE PREWEIGHED VIALS CONTAIN
B-glucuronidase type H-1 from helix*pomatia
B-GLUCURONIDASE TYPE H-5 FROM HELIX*POMA TIA
BETA-GLUCURONIDASE SOLUTION, FROM AMPULLARIA
B-GLUCURONIDASE TYPE HA-4 FROM HELIX*ASP ERSA
B-GLUCURONIDASE TYPE HP-2S FROM HELIX*PO MATIA
β-Glucoronidase from Helix pomatia, suspension
beta-Glucuronidase from Helix pomatia, ~ 5 U/ml
B-GLUCURONIDASE TYPE XI-A FROM*ESCHERICH IA COLI
BETA-GLUCURONIDASE FROM BOVINE LIVER, ~0.2 U/MG*
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE B-1
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE B-3
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE H-1
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE H-2
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE H-3
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE H-5
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE X-A
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE HA-4
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE HP-2
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE IX-A
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE L-II
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE B-10
B-glucuronidase type H-2 crude solution from heli
B-GLUCURONIDASE TYPE H-2 CRUDE SOLUTION FROM HELIX
B-GLUCURONIDASE TYPE H-3 CRUDE SOLUTION FROM HELIX
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE H-3AF
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE VII-A
BETA-D-GLUCURONIDE GLUCURONOSOHYDROLASE TYPE HP-2S
β-Glucuronidase from limpets (Patella vulgata)
B-GLUCURONIDASE TYPE HP-2 CRUDE*SOLUTION FROM HELIX
B-GLUCURONIDASE TYPE VIII-A 50%*GLYCEROL SOLUTION F
β-glucuronidase from patella vulgata (keyhole limpet)
β-Glucuronidase from Helix aspersa (garden snail)
BETA-GLUCURONIDASE FROM BOVINE LIVER, POWDER, ~0.04 U/MG*
rBeta-Glucuronidase, Beta-D-Glucuronide glucuronosohydrolase
β-Glucuronidase, molluscan from Chlamys opercularis (scallops)
beta-D-Glucuronidase, recombinant from bacteria, 50% glycerol solution
β-Glucuronidase from bovine liver,β-D-Glucuronide glucuronosohydrolase
β-Glucuronidase from Helix pomatia,β-D-Glucuronide glucuronosohydrolase
β-Glucuronidase from Escherichia coli,β-D-Glucuronide glucuronosohydrolase
β-Glucuronidase from limpets (Patella vulgata),β-D-Glucuronide glucuronosohydrolase
β-D-Glucuronide glucuronosohydrolase, β-Glucuronidase from limpets (Patella vulgata)
β-Glucuronidase, molluscan from Chlamys opercularis (scallops),β-D-Glucuronide glucuronosohydrolase
[EINECS(EC#)]

232-602-6
[Molecular Formula]

NULL
[MDL Number]

MFCD00130629
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[form ]

powder
[color ]

yellow-brown
[biological source]

limpet (Patella vulgata)
[Water Solubility ]

water: soluble
[Merck ]

13,4480
[Specific Activity]

5,000,000-20,000,000units/g protein, pH 6.8 (30 min assay)
Safety DataBack Directory
[Symbol(GHS) ]

Corrosion (GHS05)Health Hazard (GHS08)
GHS05,GHS08
[Signal word ]

Danger
[Hazard statements ]

H317-H318-H334
[Precautionary statements ]

P261-P272-P280-P302+P352-P304+P340+P312-P305+P351+P338
[Hazard Codes ]

Xn
[Risk Statements ]

42/43
[Safety Statements ]

22-36/37-45-23
[WGK Germany ]

3
[RTECS ]

LZ8990000
[F ]

3-10
[Storage Class]

10 - Combustible liquids
[Hazard Classifications]

Resp. Sens. 1
Raw materials And Preparation ProductsBack Directory
Hazard InformationBack Directory
[Chemical Properties]

Off-white or yellow powder, freely soluble in water, pI 5.1, optimum pH 4.5-5.0. Stability: After six months at 4°C, activity decreases by 10%; after twelve months, activity decreases by 20%. Addition of butanol can increase stability; turbidity does not affect activity. Inhibitors include D-glucuronic acid, D-galacturonic acid, and organic peroxides. The absorption coefficient of a 1% aqueous solution is 17.0 at 280 nm. It rapidly hydrolyzes steroidal glucuronides and other glucuronides, but not α- or β-glucosides. The enzymatic reaction is: bound β-D-glucuronide + H??O═D-glucuronic acid + alcohol.
[Uses]

In the determination of urinary steroids and of steroid conjugates in blood.
[Uses]

β-glucuronidase is used as a reporter gene in GUS assays to monitor gene expression.
[Uses]

β-Glucuronidase was used in the study of Cer-β-glucuronide synthesis and evaluation of β-glucuronidase(s) from Escherichia coli or intestinal segments to release the head group.
[General Description]

β-Glucuronidase from Escherichia coli is similar to human glucuronidase enzyme and corresponds to molecular weight close to 69-71 kDa and has an pH optimum of 6.5-7.5. It belongs to family-2 glycosyl hydrolase and has active site residues glutamic acid 394, tyrosine 468 and glutamic acid 504.
[Biochem/physiol Actions]

β-Glucuronidase (GUSB) is a lysosomal enzyme, that degrades glucuronate-containing glycosaminoglycans. β-glucuronidase, obtained from abalone has the ability to hydrolyze samples, that has high analyte concentrations. Absence of β-glucuronidase results in mucopolysaccharidosis type VII (MPSVII), which leads to lysosomal storage in the brain.
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