| Identification | Back Directory | [Name]
GLUTAMINASE | [CAS]
9001-47-2 | [Synonyms]
EC 3.5.1.2
GLUTAMINASE
l-glutaminas
l-glutaminase
Glutaminase F
GLUTAMINASE USP/EP/BP
glutamineaminohydrolase
glutaminase from E. coli
L-GLUTAMINE AMIDOHYDROLASE
glutaminase from escherichia coli
Glutaminase from Bacillus subtilis
Glutaminasefrombacillussubtilis50ug
Native Escherichia coli Glutaminase
glutaminase grade V from escherichia*coli
glutaminase grade ii from escherichia*coli
glutaminase grade vii from escherichia*coli | [EINECS(EC#)]
618-332-5 | [MDL Number]
MFCD00131193 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [form ]
lyophilized powder
| [color ]
Off-white to light yellow | [biological source]
Escherichia coli | [Specific Activity]
50-200units/mg protein |
| Hazard Information | Back Directory | [Uses]
Glutaminase from E.coli has been used:
- for the determination of glutamine from the cerebral cortex tissue extract
- for immobilization on aminopropylsilylated controlled pore glass (CPG) for determination of glutamine
- in combination with acivicin in in vitro melanoma cells and MCF-7 and OAW-42 cells for cell proliferation and invasiveness assay.
| [General Description]
Glutaminase is an amidohydrolase. It has the catalytic domain in the N-terminal and the C-terminal extension possesses STAS domain. | [Biochem/physiol Actions]
Glutaminase from Escherichia coli along with acivicin, a glutamine analog regulates proliferation and invasiveness of cancer cells. Bacterial glutaminase is implicated in increasing the life span of cancer patients by lowering the tumor burden. |
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| Company Name: |
Sigma-Aldrich
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| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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