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9002-10-2

9002-10-2 Structure

9002-10-2 Structure
IdentificationBack Directory
[Name]

TYROSINASE
[CAS]

9002-10-2
[Synonyms]

Phenolase
exMushroom
Laccase M 120
Phenol oxidase
Gluteomorphinase
Monophenol oxidase
Tyrosinase mushroom
TYROSINASE USP/EP/BP
TyrosinaseExMushroom
PHENOLASE FROM POTATO
Monophenol monooxidase
Recombinant Tyrosinase
tyrosinase from mushroom
AGARICUSBISPORUSTYROSINASE
Dihydroxyphenylalanine oxidase
Tyrosinase, Lyophilized powder
Polyphenol Oxidase (Tyrosinase)
Polyphenol Oxidase from Mushrooms
1,2-Benzenediol: oxygen oxidoreductase
TYROSINASE FROM MUSHROOM, LYOPH., >= 2000 UNITS/MG
Tyrosinase from mushroom,Catechol Oxidase, Monophenol Monooxygenase, Monophenol, dihydroxyphenylalanine:oxygen oxidoreductase, Polyphenol Oxidase
[EINECS(EC#)]

232-653-4
[Molecular Formula]

NULL
[MDL Number]

MFCD00082118
Chemical PropertiesBack Directory
[Melting point ]

89-94 °C
[storage temp. ]

−20°C
[form ]

lyophilized powder
[color ]

Light brown to brown
[biological source]

fungus (mushroom)
[Specific Activity]

≥1000unit/mg solid
[Cosmetics Ingredients Functions]

SKIN CONDITIONING
[CAS DataBase Reference]

9002-10-2
[EPA Substance Registry System]

Oxygenase, monophenol mono- (9002-10-2)
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Danger
[Hazard statements ]

H334
[Precautionary statements ]

P261-P284-P501
[Hazard Codes ]

Xn
[Risk Statements ]

42
[Safety Statements ]

22-24/25-45
[WGK Germany ]

2
[F ]

10-21
[TSCA ]

TSCA listed
Hazard InformationBack Directory
[Uses]

Tyrosinase activity has been assessed in a study that developed an alternative therapeutic agent for treating hyperpigmentation. Tyrosinase has also been used in a study to investigate the oculocutaneous albinism phenotype in the Pakistani population.
[General Description]

Isoelectric point (pI): 4.7-5
pH optimum is 6-7

Molecular weight: 128 kDa by sedimentation velocity diffusion; 133?kDa by light-scattering measurements, and 119.5 kDa by electrophoresis.

Tyrosinase is a copper-containing oxidase, which has activity for both catechols and cresol. It is responsible for browning reactions. The enzyme is reported to have two binding sites for aromatic substrates and a different binding site for oxygen-copper. The copper is probably Cu(I), with inactivation involving oxidation to Cu(II) ion.
[Biochem/physiol Actions]

Converts tyrosine to L-DOPA or tyramine to dopamine
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