| Identification | Back Directory | [Name]
T-00127-HEV1 | [CAS]
900874-91-1 | [Synonyms]
T-00127-HEV1
T00127-HEV1;T 00127 HEV1
Pyrazolo[1,5-a]pyrimidin-7-amine, 3-(3,4-dimethoxyphenyl)-2,5-dimethyl-N-[2-(4-morpholinyl)ethyl]- | [Molecular Formula]
C22H29N5O3 | [MOL File]
900874-91-1.mol | [Molecular Weight]
411.5 |
| Chemical Properties | Back Directory | [density ]
1.26±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
6.72±0.10(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta (PI4KB) inhibitor with an IC50 of 60 nM. | [Biological Activity]
Cell permeable: yes''Primary Target
PI4KIIIβ''Reversible: yes''Target IC50: 150 nM for PI4KIII&beta | [IC 50]
PI4KB: 60 nM (IC50) | [storage]
Store at -20°C | [References]
[1] Arita M, et al. Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity. J Virol. 2011 Mar;85(5):2364-72. DOI:10.1128/JVI.02249-10 |
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nanjing
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13376082704 13376082704 |
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www.linye-e.com/ |
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Merck KGaA
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www.sigmaaldrich.cn |
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