| Identification | Back Directory | [Name]
STREPTAVIDIN | [CAS]
9013-20-1 | [Synonyms]
STREPTAVIDIN
ULTRALINK SA
Polystreptavidin
STREPTAVIDIN RESIN
AGAROSE STREPTAVIDIN
STREPTAVIDIN, TYPEII
STREPTAVIDIN AGAROSE
Streptavidin avidinii
Streptomyces Avidinii
STREPTAVIDIN extrapure
WATER SEQUENCING GRADE
IMMUNOPURE STREPTAVIDIN
IMMOBILIZED STREPTAVIDIN
Streptavidin and Conjugates
AVIDIN, STREPTOMYCES AVIDINI
AVIDIN, STREPTOMYCES AVIDINII
IMMOBILIZED STREPTAVIDIN PLUS
STREPTAVIDIN-COUPLED PARTICLES
Streptavidin lyophil. salt-free
STREPTAVIDIN EXPRESSED IN E. COLI
Streptavidin, 17 units/mg protein
Streptavidin Resin(Settled Resin)
STREPTAVIDIN LYOPHIL.RESEARCH GRADE
ULTRALINK(TM) IMMOBILIZED STREPTAVIDIN
STREPTAVIDIN FROM STREPTOMYCES AVIDINII
Streptavidin, for bio, 15 units/mg protein
STREPTAVIDIN, IMMOBILIZED ON AGAROSE CL-4B
ULTRALINK(TM) IMMOBILIZED STREPTAVIDIN PLUS
STREPTAVIDIN FROM STREPTOMYCES AVIDINII, ~14 U/MG
Streptavidin-Agarose from Streptomyces avidinii
Streptavidin from Streptomyces avidinii, lyophilized
Streptavidin-Iron Oxide Particles from Streptomyces avidinii | [EINECS(EC#)]
618-481-6 | [Molecular Formula]
C14H17BrClNO2S | [MDL Number]
MFCD00082035 | [MOL File]
9013-20-1.mol | [Molecular Weight]
378.712 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C
| [solubility ]
H2O: 0.1 mg/mL, clear, colorless
| [form ]
lyophilized powder
| [color ]
White | [Water Solubility ]
Gives a clear solution at 5mg/ml in 0.1M NaCl. is soluble in water at 1 mg/mL, or in phosphate buffered saline (PBS). | [Specific Activity]
≥13units/mg protein | [InChI]
InChI=1S/C14H16ClNO2S.BrH/c15-12-6-4-5-11(9-12)14(19-10-13(17)18)16-7-2-1-3-8-16;/h4-6,9H,1-3,7-8,10H2;1H | [InChIKey]
RTWACOLFHOBGCE-UHFFFAOYSA-N | [SMILES]
[Br-].ClC1=C([H])C([H])=C([H])C(=C1[H])/C(=[N+]1/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C/1([H])[H])/SC([H])([H])C(=O)O[H] |
| Questions And Answer | Back Directory | [Background]
Streptavidin is a biotin-binding protein found in the culture broth of the bacterium Streptomyces avidinii.
Streptavidin can bind to four moles of biotin per mole of protein,and
it shows extremely high affinity, approximately 10,000-15,000 Da.
Streptavidin lacks the carbohydrate side chains present on avidin and
has an isoelectric point of 6.5 to avidin's 10 far closer to that at
which most useful biological interactions occur. As a result,
Streptavidin frequently exhibits much lower non-specific binding than
avidin does. |
| Hazard Information | Back Directory | [Uses]
Applications for enzyme-labeled (HRP, AP) streptavidin:
Enzyme immunoassays (EIA), including enzyme-linked immunsorbent assays (ELISA) with biotinylated antibodies
Cell and tissue staining (for light microscopy)
Western blotting (WB) and other membrane-based biotin detection
Applications for fluorescent (FITC, TRITC or Texas Red* Fluor-labeled) streptavidin:
Immunofluorescent assays (IFA)
Tissue staining (for fluorescence microscopy)
Blot immunostaining
Cell staining (incl. fluorescent activated cell sorting)
| [General Description]
Streptavidin is a crystalline protein isolated from the bacterium Streptomyces avidinii and possesses biotin-binding ability. It has four binding sites for biotin like avidin and binds four molecules of biotin. Streptavidin is now considered as a new type of biotin-binding protein. | [Biochem/physiol Actions]
Streptavidin is a biotin binding protein and has the ability to bind four molecules of biotin. The biotin binding pocket of streptavidin helps to interact with biotin. It can be used to enhance protein binding and multimerization. | [in vivo]
Streptavidin (8-80 mg/kg) treatment is effective in prolonging rat cardiac allografts in the high-responder WF-to-Lewis combination[2]. | Animal Model: | Lewis rats[2] | | Dosage: | 8, 12, 20, 40, 60, or 80 mg/kg | | Administration: | Administered IP for 5 consecutive days after transplantation was combined with a single dose of 0.5 mL antilymphocyte serum (ALS) on day 0 | | Result: | Prolonged cardiac allograft survival from MST of 7.3±0.5 and 8.4±0.5 days in naive and ALS-treated controls, respectively, to 15±1, 20±3, 16±3, 17±3, and 23±2 days, respectively. |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
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