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9015-68-3

9015-68-3 Structure

9015-68-3 Structure
IdentificationBack Directory
[Name]

ASPARAGINASE
[CAS]

9015-68-3
[Synonyms]

elspar
mk-965
LASPAR
leunase
paronal
l-asnase
kidrolase
colaspase
crasnitin
kisrolase
nsc-109229
EC 3.5.1.1
re82-tad-15
IUB: 3.5.4.4
ASPARAGINASE
L-asparginase
L-ASPARAGINASE
l-asparaginasi
l-asparaginasex
Crasnitin Elspar
Sustanon Injection
L-asparagise amidohydrolase
Asparaginase (usan 8ci 9ci)
L-ASPARAGINE AMIDOHYDROLASE
asparaginase from escherichia coli
Asparaginase, L-(escherichia coli)
L-Asparaginase from Escherichia coli
ASPARAGINASE GRADE V FROM ESCHERICHIA CO
L-ASPARAGINASE FROM E. COLI &
ASPARAGINASE FROM ESCHERICHIA COLICHROMA TOGRAPHICA
ASPARAGINASE FROM ESCHERICHIA COLISOLUTI ON IN GLYC
L-ASPARAGINASE FROM E. COLI, SUSPENSION, ~80 U/MG PROT.
Asparaginase from Escherichia coli,L-Asparagine Amidohydrolase
[EINECS(EC#)]

232-765-3
[Molecular Formula]

C14H17NO4S
[MDL Number]

MFCD00130565
[Molecular Weight]

295.35
Chemical PropertiesBack Directory
[Definition]

An enzyme used in the treatment of certain types of leukemia. Produced by biochemical activity of certain bacteria, yeasts, and fungi. Yields are in excess of 3500 units/g of source.
[alpha ]

D20 -30 to -32°
[storage temp. ]

2-8°C
[form ]

suspension
[Merck ]

13,841
[CAS DataBase Reference]

9015-68-3
Hazard InformationBack Directory
[Uses]

Antineoplastic.
[Brand name]

Crasnitin (Bayer); Elspar (Merck).
Safety DataBack Directory
[Hazard Codes ]

T,Xn
[Risk Statements ]

61-42/43-63
[Safety Statements ]

53-22-36/37/39-45-36/37
[RIDADR ]

3249
[WGK Germany ]

3
[RTECS ]

CI9000000
[F ]

10-21
[HazardClass ]

6.1(a)
[PackingGroup ]

II
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Agar-->TRIS BORATE EDTA BUFFER, 10X, DNASE, RNASE AND PROTEASE FREE, PH 8.3, FOR MOLECULAR BIOLOGY
Questions And AnswerBack Directory
[Description]

Asparaginase is a kind of enzyme that can be used as a medication and in food industry. It is mainly extracted from E. coli. In the medical field, it can be used for the treatment of acute lymphoblastic leukemia, acute myeloid leukemia, and non-Hodgkin’s lymphoma. This is due to that asparaginase can convert the L-asparagine into aspartate and ammonia, exhausting the available asparagine needed for leukemic cells and thus leading to cell death. In the food industry, it can be used as a processing aid in the manufacture of food to reduce the formation of acrylamide, which is a potential carcinogen through removing the asparagine which can undergo Maillard reaction during cooking to induce tumor in fried and baked food.
[References]

https://en.wikipedia.org/wiki/Asparaginase
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