| Identification | Back Directory | [Name]
2-METHYL-1,3-BENZOXAZOLE-5-CARBOXYLIC ACID | [CAS]
90322-32-0 | [Synonyms]
OTAVA-BB 1136981
2-Methyl-5-Benzoxazolecarboxylic acid
2-Methylbenzoxazole-5-carboxylic Acid
5-Benzoxazolecarboxylic acid, 2-Methyl-
2-Methyl-benzooxazole-6-carboxylic acid
2-METHYL-BENZOOXAZOLE-5-CARBOXYLIC ACID
2-Methylbenzo[d]oxazole-5-carboxylic acid
2-METHYL-1,3-BENZOXAZOLE-5-CARBOXYLIC ACID | [Molecular Formula]
C9H7NO3 | [MDL Number]
MFCD09759125 | [MOL File]
90322-32-0.mol | [Molecular Weight]
177.16 |
| Chemical Properties | Back Directory | [Melting point ]
186-188℃ | [Boiling point ]
353.5±15.0 °C(Predicted) | [density ]
1.38 | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
3.53±0.30(Predicted) | [Appearance]
Light brown to off-white Solid |
| Hazard Information | Back Directory | [Synthesis]
). The reaction mixture was stirred at 25 °C for 3 hours. Upon completion of the reaction, the mixture was acidified to pH < 7 with dilute hydrochloric acid and a white solid was precipitated. The solid product was collected by filtration, washed with deionized water and subsequently dried under vacuum. Finally, the crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=1:1, v/v) to afford the target compound 2-methyl-5-benzoxazolecarboxylic acid (0.30 g, 65% yield) as a white solid. | [References]
[1] Patent: WO2016/100184, 2016, A1. Location in patent: Paragraph 00321-00322 |
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