| Identification | Back Directory | [Name]
Schizophyllan | [CAS]
9050-67-3 | [Synonyms]
Sixofilan
Sonifilan
Sizofuran
Sizofiran
Shizophyllan
SCHIZOPHYLLAN
Schizophyllane
Schizophyllan (SPG)
(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,5-triol
(2S,3R,4S,5S,6R)-2-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-2-[(2R,3R,4S,5R,6R)-2,3,5-trihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
(2S,3R,4S,5S,6R)-2-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-2-[(2R,3R,4S,5R,6R)-2,3,5-trihydroxy-6-methylol-tetrahydropyran-4-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-4-yl]oxy-6-methylol-tetrahydropyran-3,4,5-triol | [EINECS(EC#)]
202-316-6 | [Molecular Formula]
C24H42O21 | [MOL File]
9050-67-3.mol | [Molecular Weight]
666.578 |
| Chemical Properties | Back Directory | [Description]
Schizophyllan is an immunostirnulant polysaccharide related to lentinan, isolated from the culture filtrate of Schizophyllum commune. It is useful in combination with other antineoplastic treatments in the management of carcinomas of the lungs, stomach, uterus and breasts. | [Cosmetics Ingredients Functions]
HUMECTANT | [InChIKey]
WDQLRUYAYXDIFW-OZFNHEKHNA-N | [CAS DataBase Reference]
9050-67-3 |
| Hazard Information | Back Directory | [Originator]
Taito (Japan) | [Uses]
Schizophyllan (SPG), a member of the β-glucan family, is an exopolysaccharide with antineoplastic, antibacterial activities and antiparasitic properties. Schizophyllan can be used for petroleum recovery, a thickener for cosmetic lotions, oxygen impermeable films for food preservation, and high-value pharmaceutical applications[1][2]. | [Brand name]
SONlFILAN | [References]
[1] Mochizuki S, et al. Oligonucleotide delivery to antigen presenting cells by using schizophyllan. Drug Metab Pharmacokinet. 2022 Feb;42:100434. DOI:10.1016/j.dmpk.2021.100434
[2] Zhang Y, et al. Schizophyllan: A review on its structure, properties, bioactivities and recent developments[J]. Bioactive Carbohydrates and Dietary Fibre, 2013, 1(1): 53-71. |
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