ChemicalBook--->CAS DataBase List--->90566-53-3

90566-53-3

90566-53-3 Structure

90566-53-3 Structure
IdentificationMore
[Name]

Fluticasone
[CAS]

90566-53-3
[Synonyms]

(6s,9s,10s,11s,13s,14s,16r,17r)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
FLUTICASONE
FluticasonePropionate98.5%
Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6.alpha.,11.beta.,16.alpha.,17.alpha.)-
(6S,9S,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(fluoromethylsulfanylcarbonyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
6α,9-Difluoro-11β,17-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioic acid S-(fluoromethyl) ester
6α,9-Difluoro-16α-methyl-11β-hydroxy-17-hydroxy-3-oxoandrosta-1,4-diene-17β-carbothioic acid S-(fluoromethyl) ester
[Molecular Formula]

C25H31F3O5S
[MDL Number]

MFCD01862254
[Molecular Weight]

500.57
[MOL File]

90566-53-3.mol
Chemical PropertiesBack Directory
[Melting point ]

237-239 °C
[Boiling point ]

553.2±50.0 °C(Predicted)
[density ]

1.37±0.1 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Acetonitrile (Slightly), Chloroform (Slightly)
[form ]

Solid
[pka]

11.66±0.70(Predicted)
[color ]

White to Off-White
[Stability:]

Hygroscopic, Unstable in Solution
[CAS DataBase Reference]

90566-53-3(CAS DataBase Reference)
Safety DataBack Directory
[Hazardous Substances Data]

90566-53-3(Hazardous Substances Data)
Hazard InformationBack Directory
[Uses]

therapeutic for asthma and allergic rhinitis Flonase
[Definition]

ChEBI: A trifluorinated corticosteroid used in the form of its propionate ester for treatment of allergic rhinitis.
[Brand name]

Cutivate (Altana); Flonase (GlaxoSmithKline); Flovent (GlaxoSmithKline).
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