| Chemical Properties | Back Directory | [Boiling point ]
467.5±47.0 °C(Predicted) | [density ]
1.242±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
0.81±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with an IC50 value of 15.9 μM for recombinant HAT p300/CBP-associated factor (PCAF). NSC 694623 has antiproliferative activity against certain cancer cells. NSC 694623 can be used for researching anticancer[1]. | [IC 50]
PCAF: 15.9 μM (IC50) | [References]
[1] Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89. DOI:10.1016/j.bmc.2011.01.063 |
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