| Identification | Back Directory | [Name]
3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontanoic acid | [CAS]
908258-58-2 | [Synonyms]
MPEG10-CH2COOH
m-PEG11-CH2CO2H
mPEG10-acetic acid
3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontanoic acid
2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid | [Molecular Formula]
C23H46O13 | [MDL Number]
MFCD16619366 | [MOL File]
908258-58-2.mol | [Molecular Weight]
530.6 |
| Hazard Information | Back Directory | [Description]
m-PEG11-CH2COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| Spectrum Detail | Back Directory | [Spectrum Detail]
3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontanoic acid(908258-58-2)1HNMR
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Nextpeptide Inc
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Bide Pharmatech Ltd.
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