ChemicalBook--->CAS DataBase List--->1258596-39-2

1258596-39-2

1258596-39-2 Structure

1258596-39-2 Structure
IdentificationBack Directory
[Name]

mPEG11-Br
[CAS]

1258596-39-2
[Synonyms]

mPEG11-Br
[Molecular Formula]

C23H47BrO11
[MDL Number]

MFCD31656939
[MOL File]

1258596-39-2.mol
[Molecular Weight]

579.52
Chemical PropertiesBack Directory
[Boiling point ]

564.5±45.0 °C(Predicted)
[density ]

1.179±0.06 g/cm3(Predicted)
[storage temp. ]

Store at Room Tem.
Hazard InformationBack Directory
[Uses]

m-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Biological Activity]

m-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[IC 50]

PEGs
[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Spectrum DetailBack Directory
[Spectrum Detail]

mPEG11-Br(1258596-39-2)1HNMR
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