| Identification | Back Directory | [Name]
GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE | [CAS]
908844-75-7 | [Synonyms]
M871
GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE
TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLU-HIS-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2
L-Alaninamide, L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-α-glutamyl-L-histidyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl- | [Molecular Formula]
C108H163N27O28 | [MDL Number]
MFCD11112194 | [MOL File]
908844-75-7.mol | [Molecular Weight]
2287.61 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at -20°C | [solubility ]
Soluble to 1 mg/ml in 30% acetonitrile | [form ]
Powder | [color ]
White to off-white | [Water Solubility ]
Soluble to 1 mg/ml in water | [Sequence]
H2N-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Glu-His-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2 |
| Hazard Information | Back Directory | [Description]
Selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM for GAL2 and GAL1 receptors respectively). Blocks the pro-nociceptive effect of GAL2 receptor agonists. | [Uses]
M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is a selective galanin receptor type 2 (GalR2) antagonist. M871 exhibits Ki values of 13.1 nM and 420 nM for GalR2 and GalR1, respectively. M871 can be used for research on GalR2-related diseases (such as epilepsy, pain)[1]. | [storage]
Desiccate at -20°C | [References]
[1] U. E. Sollenberg, et al. M871—A Novel Peptide Antagonist Selectively Recognizing the Galanin Receptor Type 2. Int J Pept Res Ther. 2006;12:2965-2982. |
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BOC Sciences
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https://www.bocsci.com |
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