| Identification | Back Directory | [Name]
EXOTOXIN A | [CAS]
91262-95-2 | [Synonyms]
EXOTOXIN A
PSEUDOMONAS EXOTOXIN A
EXOTOXIN A, PSEUDOMONAS AERUGINOSA
Pseudomonas aeruginosa exotoxin PE38
Toxin A, exo- (Pseudomonas aeruginosa reduced)
PSEUDOMONAS EXOTOXIN A FROM PSEUDOMONAS AERUGINOSA
Exotoxin A, Pseudomonas aeruginosa - CAS 91262-95-2 - Calbiochem | [MDL Number]
MFCD00132134 |
| Safety Data | Back Directory | [Hazard Codes ]
T,T+ | [Risk Statements ]
23/24/25-26/27/28 | [Safety Statements ]
45-36/37-28 | [RIDADR ]
UN 3462 6.1/PG 2 | [WGK Germany ]
3 | [RTECS ]
LF2991000 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral |
| Hazard Information | Back Directory | [Uses]
Exotoxin A, Pseudomonas aeruginosa is protein synthesis inhibitor via Bak expression level regulation. | [General Description]
Pseudomonas exotoxin A is secreted by Pseudomonas aeruginosa. It is a member of the family mono-ADP-ribosyltransferases. | [Biochem/physiol Actions]
Pseudomonas exotoxin A functions as an anticancer agent.It catalyses the transfer of ADP-ribose moiety of NAD+ to the histidine imidazole ring of diphthamide.Shown to be toxic to animals and to cell lines, and to inhibit protein synthesis via ADP ribosylation of elongation factor 2. |
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