| Identification | Back Directory | [Name]
[2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone | [CAS]
913186-74-0 | [Synonyms]
LY 2087101
(2-Amino-5-keto)thiazole)
[2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone
Methanone, [2-[(4-fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienyl-
[2-(4-Fluoro-phenylamino)-4-methyl-thiazol-5-yl]-thiophen-3-yl-methanone | [Molecular Formula]
C15H11FN2OS2 | [MDL Number]
MFCD19690940 | [MOL File]
913186-74-0.mol | [Molecular Weight]
318.39 |
| Chemical Properties | Back Directory | [Melting point ]
160 - 163°C | [Boiling point ]
449.1±55.0 °C(Predicted) | [density ]
1.407±0.06 g/cm3(Predicted) | [storage temp. ]
Store at +4°C | [solubility ]
DMSO: soluble20mg/mL, clear | [form ]
powder | [pka]
2.71±0.10(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
LY 2087101 is a positive allosteric Nicotinic acetylcholine receptor (nAChR) modulators. nAChRs are found in the CNS and they respond to neurotransmitter acetylcholine. | [Biological Activity]
LY 2087101 is a selective positive allosteric potentiator of α7 and α4β2 nicotinic acetylcholine receptors (nAChRs). LY 2087101 was shown to not enhance the activity of α3β4 subtype nAChRs. | [storage]
Store at -20°C |
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