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914800-65-0

914800-65-0 Structure

914800-65-0 Structure
IdentificationBack Directory
[Name]

L-Glutamic acid, N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-, disodium salt (9CI)
[CAS]

914800-65-0
[Synonyms]

Folic Acid Impurity 46 Disodium Salt
10-Formyltetrahydrofolic acid disodium
10-Formyltetrahydrofolate (sodium salt) (technical grade)
10-Formyl-5,6,7,8-tetrahydro Folic Acid Disodium Salt (Technical Grade)
(4-(N-((2-Amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)formamido)benzoyl)-L-glutamic acid, Disodium Salt
L-Glutamic acid, N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-, disodium salt (9CI)
[Molecular Formula]

C20H23N7O7.2Na
[MOL File]

914800-65-0.mol
[Molecular Weight]

517.403
Chemical PropertiesBack Directory
[Melting point ]

>286°C (dec.)
[storage temp. ]

Amber Vial, Hygroscopic, -86°C Freezer, Under inert atmosphere
[solubility ]

Methanol (Slightly, Sonicated), Water (Slightly)
[form ]

Solid
[color ]

Light Brown to Very Dark Brown
[Stability:]

Hygroscopic, Light Sensitive, Temperature Sensitive
Hazard InformationBack Directory
[Uses]

10-Formyl-5,6,7,8-tetrahydro Folic Acid Disodium Salt is the disodium salt of F701085, which is a Folic Acid (F680300) derivative. Folic Acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.10-Formyl-5,6,7,8-tetrahydro Folic Acid Disodium Salt is also used in the diagnosis and prevention and therapy of cerebral folate dificiency in relation to formation of folate receptor autoantibodies and treatment with reduced folate and antioxidants.
[in vivo]

10-Formyltetrahydrofolic acid disodium in the liver of male Sprague-Dawley rats increases significantly after 30 and 60 minutes by administration of 1.3 mmol/kg methionine[1].

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