| Identification | Back Directory | [Name]
2-VINYL-4-QUINAZOLINOL | [CAS]
91634-12-7 | [Synonyms]
STIMA 1
2-VINYL-4-QUINAZOLINOL
2-Vinylquinazolin-4(3H)-one
2-vinylquinazolin-4(1H)-one
2-VINYL-3H-QUINAZOLIN-4-ONE
2-ethenyl-1H-quinazolin-4-one
4(3H)-Quinazolinone, 2-ethenyl-
2-Ethenyl-3,4-dihydroquinazolin-4-one | [Molecular Formula]
C10H8N2O | [MDL Number]
MFCD04037877 | [MOL File]
91634-12-7.mol | [Molecular Weight]
172.18 |
| Chemical Properties | Back Directory | [Melting point ]
>200°C (dec.) | [Boiling point ]
315.4±25.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
1.91±0.20(Predicted) | [color ]
White to Off-White | [Stability:]
Light Sensitive |
| Hazard Information | Back Directory | [Uses]
STIMA-1 can stimulate mutant p53 DNA binding in vitro and induce expression of p53 target proteins and trigger apoptosis in mutant p53-expressing human tumor cells[1]. | [References]
[1] Nicole Zache, et al. Mutant p53 targeting by the low molecular weight compound STIMA-1. Mol Oncol. 2017 May;11(5):595. DOI:10.1002/1878-0261.12065 |
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