| Identification | Back Directory | [Name]
(-)-5,5',7-Trihydroxy-2'-methyl-2'-(4-methyl-3-pentenyl)-2,6'-bi[2H-1-benzopyran]-4(3H)-one | [CAS]
92280-12-1 | [Synonyms]
Sanggenon N
Sanggenone N
(-)-5,5,7-Trihydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2,6-bi[2H-1-benzopyran]-4(3H)-one
(-)-5,5',7-Trihydroxy-2'-methyl-2'-(4-methyl-3-pentenyl)-2,6'-bi[2H-1-benzopyran]-4(3H)-one
[2,6'-Bi-2H-1-benzopyran]-4(3H)-one, 5,5',7-trihydroxy-2'-methyl-2'-(4-methyl-3-pentenyl)- (9CI) | [Molecular Formula]
C25H26O6 | [MDL Number]
MFCD32858215 | [MOL File]
92280-12-1.mol | [Molecular Weight]
422.47 |
| Hazard Information | Back Directory | [Description]
Sanggenon N shows protective effects on t-BHP-induced oxidative stress with the EC50 value of 23.45 ± 4.72 uM.
Sanggenon N inhibits lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages. | [Uses]
Sanggenon N is an isoprenylated flavonoid that can be isolated from the root bark of Morus alba.Sanggenon N has hepatoprotective activities on t-BHP-induced cell cytotoxicity in HepG2 cells with an EC50 of 23.45 μM[1]. | [target]
NO | [References]
[1] Jung JW, et.al. Isoprenylated flavonoids from the root bark of Morus alba and their hepatoprotective and neuroprotective activities. Arch Pharm Res. 2015 Nov;38(11):2066-75. DOI:10.1007/s12272-015-0613-8 |
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