ChemicalBook--->CAS DataBase List--->92451-01-9

92451-01-9

92451-01-9 Structure

92451-01-9 Structure
IdentificationBack Directory
[Name]

MONO-METHYL POLYETHYLENE GLYCOL 5'000ACETIC ACID N-SUCCINIMIDYL ESTER
[CAS]

92451-01-9
[Synonyms]

MPEG-SC
Sunbright ME 020AS
Sunbright ME 050AS
MPEGn-SCM 2K, 5K, 10K, 20K
SUCCINIMIDYL ESTER OF CARBOXYMETHYL-PEG
Methoxypoly(ethylene glycol) succiniMidyl ester
mPEG-SCM(mPEG-Succinimidyl Carboxy Methyl ester)
Methoxypoly(ethylene glycol) succinimidyl carbonate
O-[(N-succinimidyloxycarbonyl)me]-O'-me-polyeth.glycol 5000
METHOXYPOLYETHYLENE GLYCOL 5,000 ACETIC ACID N-SUCCINIMIDYL ESTER
M-SCM-5000(METHOXY PEG SUCCINIMIDYL CARBOXYMETHYL ESTER, MW 5000)
O-[(N-Succinimidyloxycarbonyl)methyl]-O'-methylpolyethylene glycol
MONO-METHYL POLYETHYLENE GLYCOL 5'000ACETIC ACID N-SUCCINIMIDYL ESTER
MONO-METHYL POLYETHYLENE GLYCOL 5,000 ACETIC ACID N-SUCCINIMIDYL ESTER
O-[(N-SUCCINIMIDYLOXYCARBONYL)-METHYL]-O'-METHYL-POLYETHYLENE GLYCOL 5'000
Poly(oxy-1,2-ethanediyl),a-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-w-Methoxy-
MONO-METHYL POLYETHYLENE GLYCOL 5'000ACETIC ACID N-SUCCINIMIDYL ESTER ISO 9001:2015 REACH
Succinimidyl ester of carboxymethyl-PEG, mono-Methyl polyethylene glycol 5μ000 acetic acid N-succinimidyl ester
[Molecular Formula]

C11H19NO8
[MDL Number]

MFCD01867746
[MOL File]

92451-01-9.mol
[Molecular Weight]

293.27
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

Solid
[color ]

White to off-white
[α-end]

methoxy
[Ω-end]

NHS ester
[InChI]

InChI=1S/C8H11NO6.C3H8O2/c10-3-4-14-5-8(13)15-9-6(11)1-2-7(9)12;1-5-3-2-4/h10H,1-5H2;4H,2-3H2,1H3
[InChIKey]

NYXRHTOXAYVBMV-UHFFFAOYSA-N
[SMILES]

O(C(C([H])([H])OC([H])([H])C([H])([H])O[H])=O)N1C(C([H])([H])C([H])([H])C1=O)=O.O(C([H])([H])[H])C([H])([H])C([H])([H])O[H]
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[F ]

3-10-23
Hazard InformationBack Directory
[Uses]

m-PEG-NHS ester (MW 2000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
[References]

[1] Jin M, et al. Preparation of pegylated lumbrokinase and an evaluation of its thrombolytic activity both in vitro and in vivo[J]. Acta Pharmaceutica Sinica B, 2013, 3(2): 123-129.
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