Identification | Back Directory | [Name]
6-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)-7H-purine | [CAS]
924764-38-5 | [Synonyms]
NPD7155 NPD-7155 NPD 7155 6-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)-7H-purine 6-Azabicyclo[3.2.1]octane, 1,3,3-trimethyl-6-(9H-purin-6-yl)- | [Molecular Formula]
C15H21N5 | [MOL File]
924764-38-5.mol | [Molecular Weight]
271.36 |
Hazard Information | Back Directory | [Description]
NPD7155 is a competitive MTH1 inhibitor. | [Uses]
NPD7155 is a purine-based competitive inhibitor of MTH1, designed to target cancer cells while exhibiting off-target effects that contribute to its cytotoxicity. | [References]
[1] Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival DOI:10.1038/srep26521 |
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