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924764-38-5

924764-38-5 Structure

924764-38-5 Structure
IdentificationBack Directory
[Name]

6-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)-7H-purine
[CAS]

924764-38-5
[Synonyms]

NPD7155
NPD-7155
NPD 7155
6-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)-7H-purine
6-Azabicyclo[3.2.1]octane, 1,3,3-trimethyl-6-(9H-purin-6-yl)-
[Molecular Formula]

C15H21N5
[MOL File]

924764-38-5.mol
[Molecular Weight]

271.36
Hazard InformationBack Directory
[Description]

NPD7155 is a competitive MTH1 inhibitor.
[Uses]

NPD7155 is a purine-based competitive inhibitor of MTH1, designed to target cancer cells while exhibiting off-target effects that contribute to its cytotoxicity.
[References]

[1] Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival DOI:10.1038/srep26521
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