| Identification | Back Directory | [Name]
Benzenemethanol, α-pentyl-3-(2-quinolinylmethoxy)-, hydrochloride (1:1) | [CAS]
92532-23-5 | [Synonyms]
REV 5901A
Benzenemethanol, α-pentyl-3-(2-quinolinylmethoxy)-, hydrochloride (1:1) | [Molecular Formula]
C22H26ClNO2 | [MOL File]
92532-23-5.mol | [Molecular Weight]
371.91 |
| Hazard Information | Back Directory | [Uses]
REV 5901 hydrochloride is a competitive and orally active antagonist of leukotriene receptor, with a Ki of 0.7 μM. REV 5901 hydrochloride is also a 5-lipoxygenase inhibitor. REV 5901 hydrochloride can be used for the research of asthma in which leukotriene release be involved[1][2]. | [References]
[1] Inwegen RGV, et, al. REV 5901: an orally effective peptidoleukotriene antagonist, detailed biochemical/pharmacological profile. J Pharmacol Exp Ther. 1987 Apr;241(1):117-24. PMID:2437284
[2] Anderson G, et, al. Effects of REV 5901, a 5-lipoxygenase inhibitor and leukotriene antagonist, on pulmonary responses to platelet activating factor in the guinea-pig. Br J Pharmacol. 1988 Aug;94(4):1115-22. DOI:10.1111/j.1476-5381.1988.tb11629.x |
|
|