| Identification | Back Directory | [Name]
ipsapirone | [CAS]
92589-98-5 | [Synonyms]
Ipsapirone HCl
Unii-08R5U8pyvo
Ipsapirone hydrochloride
1,2-Benzisothiazol-3(2H)-one, 2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, 1,1-dioxide, monohydrochloride | [Molecular Formula]
C19H24ClN5O3S | [MOL File]
92589-98-5.mol | [Molecular Weight]
437.94 |
| Hazard Information | Back Directory | [Uses]
Anti-anxiety agent
. | [References]
[1] T GLASER J T. Binding of the putative anxiolytic TVX Q 7821 to hippocampal 5-hydroxytryptamine (5-HT) recognition sites.[J]. Naunyn-Schmiedeberg’s archives of pharmacology, 1985, 329 3: 211-215. DOI: 10.1007/bf00501870
[2] TREVOR SHARP David G G S Steven R Bramwell. 5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis[J]. British Journal of Pharmacology, 1989, 96 2: 283-290. DOI: 10.1111/j.1476-5381.1989.tb11815.x
[3] JUNJI ICHIKAWA Herbert Y M. The effect of ipsapirone and S(−)-pindolol on dopamine release in rat striatum and nucleus accumbens[J]. Brain Research, 1999, 842 2: Pages 445-451. DOI: 10.1016/s0006-8993(99)01876-4
[4] JÖRG TRABER . Brain serotonin receptors as a target for the putative anxiolytic TVX Q 7821[J]. Brain Research Bulletin, 1984, 12 6: Pages 741-744. DOI: 10.1016/0361-9230(84)90155-2
[5] JEFFREY L RAUSCH. Temperature Regulation in Depression: Functional 5HT1A Receptor Adaptation Differentiates Antidepressant Response[J]. Neuropsychopharmacology, 2006, 31 10: 2274-2280. DOI: 10.1038/sj.npp.1301088 |
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