| Identification | Back Directory | [Name]
N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride | [CAS]
926023-82-7 | [Synonyms]
AMTB
AMTB NEW
AMTB HCl
AMTB hydrate
AMTB hydrochloride
N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamidehydrochloride
N-(3-aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)-benzamide hydrochloride (1:1) hyclate | [Molecular Formula]
C23H26N2O2S.HCl | [MDL Number]
MFCD18086917 | [MOL File]
926023-82-7.mol | [Molecular Weight]
431 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at +4°C | [solubility ]
DMSO: ≥10mg/mL | [form ]
powder | [color ]
white to tan | [InChI]
InChI=1S/C23H26N2O2S.ClH/c1-18-7-4-8-19(15-18)17-27-22-11-3-2-10-21(22)23(26)25(13-6-12-24)16-20-9-5-14-28-20;/h2-5,7-11,14-15H,6,12-13,16-17,24H2,1H3;1H | [InChIKey]
UDXGBANGPYONOK-UHFFFAOYSA-N | [SMILES]
C(C1C=CC=CC=1OCC1C=CC=C(C)C=1)(=O)N(CCCN)CC1SC=CC=1.Cl |
| Hazard Information | Back Directory | [Uses]
AMTB hydrate has been used as an inhibitor of transient receptor potential cation channel, subfamily melastatin, member 8 (TRPM8) in breast cancer cells and murine T cells. | [Biochem/physiol Actions]
AMTB is a 2-benzyloxy-benzoic acid amide derivative, which also inhibits voltage-gated sodium channels (Nav) and their isoforms. | [storage]
Room temperature (desiccate) |
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