| Identification | Back Directory | [Name]
3H-Imidazo[4,5-b]pyridine, 2-cyclohexyl-5,7-diphenyl- | [CAS]
929641-63-4 | [Synonyms]
LUF5981
LUF-5981
LUF 5981
3H-Imidazo[4,5-b]pyridine, 2-cyclohexyl-5,7-diphenyl- | [Molecular Formula]
C24H23N3 | [MOL File]
929641-63-4.mol | [Molecular Weight]
353.46 |
| Chemical Properties | Back Directory | [Melting point ]
210-213 °C(Solv: chloroform (67-66-3); ethanol (64-17-5)) | [Boiling point ]
626.3±43.0 °C(Predicted) | [density ]
1.177±0.06 g/cm3(Predicted) | [pka]
10.44±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
LUF5981 is a relatively potent adenosine A2A receptor (A2A) antagonist with pIC50 value of 6.7[1]. | [References]
[1] Fan Fan, et al. The integration of pharmacophore-based 3D QSAR modeling and virtual screening in safety profiling: A case study to identify antagonistic activities against adenosine receptor, A2A, using 1,897 known drugs. PLoS One. 2019 Jan 3;14(1):e0204378. DOI:10.1371/journal.pone.0204378 |
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